Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJQ7XD)

Drug Name

Recombinant TSH superagonists Drug Info

Synonyms

Recombinant TSH superagonists (thyroid cancer); TR-1401; TR-1402; Recombinant TSH superagonists (thyroid cancer), Trophogen; TSH superagonist (thyroid cancer/goiter), Trophogen; Thyroid stimulating hormone superagonist (thyroid cancer/goiter), Trophogen

Indication

Disease Entry	ICD 11	Status	REF
Thyroid cancer	2D10	Investigative	[1]

Cross-matching ID

TTD Drug ID: DMJQ7XD

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Thyrotropin receptor (TSHR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Thyrotropin	DMJ47QC	Hypothyroidism	5A00	Approved	[2]
Thyrotropin Alfa	DMMYLTI	Thyroid cancer	2D10	Approved	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thyrotropin receptor (TSHR)	TT6NYJA	TSHR_HUMAN	Agonist	[1]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 255).
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3	Pharmacological profiles and clinical effects of recombinant human thyrotropin alfa (Thyrogen) Intramuscular Injection 0.9 mg). Nippon Yakurigaku Zasshi. 2009 Jul;134(1):28-34.