Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJS8V3)

Drug Name

Disufenton sodium Drug Info

Synonyms

Cerovive; ARL-16556; CPI-22; CXY-059; HPN-07; NXY-059; NXY-059G; OKN-007; S-PBN; Nitrones (cancer), Oklahoma Medical Research Foundation; Nitrones, Renovis/AstraZeneca; PBN derivatives, Renovis/AstraZeneca; Spin trap agents, Renovis/AstraZeneca

Indication

Disease Entry	ICD 11	Status	REF
Ischemia	8B10-8B11	Phase 3	[1]
Recurrent glioblastoma	2A00.00	Phase 1	[2]

Cross-matching ID

PubChem CID: 6440181
TTD Drug ID: DMJS8V3

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Free radical (FRD)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
RRx-001	DMQM2FH	Small-cell lung cancer	2C25.Y	Phase 3	[4]
SM-88	DMD9ISG	Pancreatic cancer	2C10	Phase 2/3	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Free radical (FRD)	TT8E7Z0	NOUNIPROTAC	Modulator	[3]

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References

1	ClinicalTrials.gov (NCT00061022) Safety and Effectiveness of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	NXY-059, a free radical--trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species. Stroke. 2001 Jan;32(1):190-8.
4	Dinitroazetidines are a novel class of anticancer agents and hypoxia-activated radiation sensitizers developed from highly energetic materials. Cancer Res. 2012 May 15;72(10):2600-8.