Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMKG7J2)

Drug Name

lysophosphatidylserine Drug Info

Synonyms

lysoPS; lysophosphatidyl-L-serine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
G-protein coupled receptor 174 (GPR174)	TTYUB4M	GP174_HUMAN	Agonist	[2]
G-protein coupled receptor 34 (GPR34)	TTVXSTQ	GPR34_HUMAN	Agonist	[3]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4064).
2	TGFalpha shedding assay: an accurate and versatile method for detecting GPCR activation. Nat Methods. 2012 Oct;9(10):1021-9.
3	GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position. J Biochem. 2012 May;151(5):511-8.