Details of the Drug-Related molecule(s) Interaction Atlas

1-Benzyl-3-bromo-1H-pyrrole-2,5-dione Drug Info

1-benzyl-3-bromo-1H-pyrrole-2,5-dione; 112749-49-2; 3-bromo-2,5-dihydro-1-benzyl-1h-pyrrole-2,5-dione; SCHEMBL4848605; CHEMBL3653656; LLBVECSKMXUDOT-UHFFFAOYSA-N; BDBM136369; ZINC34614650; AKOS027470535; 1-BENZYL-3-BROMOPYRROLE-2,5-DIONE; US8865750, CCG- 203780

Cross-matching ID

PubChem CID

15628904

TTD Drug ID

DML8RVS

General Information of Drug (ID: DML8RVS)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Regulator of G-protein signaling 8 (RGS8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1-Benzyl-3-p-tolyl-1H-pyrrole-2,5-dione	DMWY9GM	N. A.	N. A.	Patented	[1]
thiadiazolidinone (TDZD) deriv. 6	DM9CF45	Discovery agent	N.A.	Investigative	[2]
CCG-50014	DMUQJ6X	Discovery agent	N.A.	Investigative	[2]
RGS4 inhibitor 13	DM4XVLB	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Regulator of G-protein signaling 8 (RGS8)	TTWME23	RGS8_HUMAN	Inhibitor	[1]

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References

1	Small molecule inhibitors of RGS proteins. US8865750.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2813).