Details of the Drug-Related molecule(s) Interaction Atlas

Betais-sulfonylamino derivative 1 Drug Info

PMID28627961-Compound-40

Cross-matching ID

PubChem CID

42596932

TTD Drug ID

DMMCDR7

General Information of Drug (ID: DMMCDR7)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Prostaglandin E synthase (PTGES)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AAD-2004	DMG4RK0	Alzheimer disease	8A20	Phase 1	[2]
Carboxylic acid derivative 1	DM86E2P	Angiogenesis disorder	BE2Z	Patented	[1]
Phthalazinone derivative 1	DMNA941	N. A.	N. A.	Patented	[1]
Benzamide derivative 18	DMD7640	N. A.	N. A.	Patented	[1]
Benzimidazole derivative 13	DMV4DQI	N. A.	N. A.	Patented	[1]
Benzamide derivative 16	DMOAXKF	N. A.	N. A.	Patented	[1]
Imidazopyridine derivative 5	DMUKBGD	N. A.	N. A.	Patented	[1]
Imidazopyridine derivative 6	DMA0V4F	N. A.	N. A.	Patented	[1]
PMID28627961-Compound-22	DM36P7T	N. A.	N. A.	Patented	[1]
Imidazole benzamide derivative 1	DM0SOKJ	Knee pain	ME82	Patented	[1]
------------------------------------------------------------------------------------


⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin E synthase (PTGES)	TTYLQ8V	PTGES_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Sep;27(9):1047-1059.
2	Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis. J Neurochem. 2012 Sep;122(5):952-61.