Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOFTRE)

Drug Name
Cizolirtine Drug Info
Synonyms Cizolirtine [INN]; N,N-dimethyl-2-[(2-methylpyrazol-3-yl)-phenylmethoxy]ethanamine; N,N-dimethyl-2-[(R)-(2-methylpyrazol-3-yl)-phenylmethoxy]ethanamine
Indication
Disease Entry ICD 11 Status REF
Neuropathic pain 8E43.0 Phase 2 [1]
Therapeutic Class
Analgesics
Cross-matching ID
PubChem CID
132412
CAS Number
CAS 142155-43-9
TTD Drug ID
DMOFTRE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Calcitonin gene-related peptide 1 (CALCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
FV-Aib-TDVGPFAF DMEI890 Discovery agent N.A. Investigative [2]
Ac-WVTH[hArg]LAGLLS[hArg]SGGVVRKNFVPTDVGPFAF-NH2 DM19NMF Discovery agent N.A. Investigative [2]
Ac-WVEHRLKGELSRKGGVV[hArg]KNFVPTDVGPFAF-NH2 DM9W21L Discovery agent N.A. Investigative [2]
VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 DMJ2PG1 Discovery agent N.A. Investigative [2]
Ac-WVTHQLAGLLSQSGGVVRKNFVPTDVGPFAF-NH2 DM3BUP6 Discovery agent N.A. Investigative [2]
Ac-VTHRLAGLLSRSGGVVKNNFVPTDVGPFAF-NH2 DMO0W9V Discovery agent N.A. Investigative [2]
Ac-WVTHRLAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 DMSMVK4 Discovery agent N.A. Investigative [2]
Ac-WVTH[Cit]LAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 DMR1N53 Discovery agent N.A. Investigative [2]
Ac-WVTHRLAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 DMKO982 Discovery agent N.A. Investigative [2]
Ac-WVTH[Cit]LAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 DMJU4AM Discovery agent N.A. Investigative [2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calcitonin gene-related peptide 1 (CALCA) TTVSFJW CALCA_HUMAN Inhibitor [1]

References

1 Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26.
2 Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor. J Med Chem. 2008 Dec 25;51(24):7889-97.