General Information of Drug (ID: DMOFTRE)

Drug Name
Cizolirtine Drug Info
Synonyms Cizolirtine [INN]; N,N-dimethyl-2-[(2-methylpyrazol-3-yl)-phenylmethoxy]ethanamine; N,N-dimethyl-2-[(R)-(2-methylpyrazol-3-yl)-phenylmethoxy]ethanamine
Indication
Disease Entry ICD 11 Status REF
Neuropathic pain 8E43.0 Phase 2 [1]
Therapeutic Class
Analgesics
Cross-matching ID
PubChem CID
132412
CAS Number
CAS 142155-43-9
TTD Drug ID
DMOFTRE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
FV-Aib-TDVGPFAF DMEI890 Discovery agent N.A. Investigative [2]
Ac-WVTH[hArg]LAGLLS[hArg]SGGVVRKNFVPTDVGPFAF-NH2 DM19NMF Discovery agent N.A. Investigative [2]
Ac-WVEHRLKGELSRKGGVV[hArg]KNFVPTDVGPFAF-NH2 DM9W21L Discovery agent N.A. Investigative [2]
VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 DMJ2PG1 Discovery agent N.A. Investigative [2]
Ac-WVTHQLAGLLSQSGGVVRKNFVPTDVGPFAF-NH2 DM3BUP6 Discovery agent N.A. Investigative [2]
Ac-VTHRLAGLLSRSGGVVKNNFVPTDVGPFAF-NH2 DMO0W9V Discovery agent N.A. Investigative [2]
Ac-WVTHRLAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 DMSMVK4 Discovery agent N.A. Investigative [2]
Ac-WVTH[Cit]LAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 DMR1N53 Discovery agent N.A. Investigative [2]
Ac-WVTHRLAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 DMKO982 Discovery agent N.A. Investigative [2]
Ac-WVTH[Cit]LAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 DMJU4AM Discovery agent N.A. Investigative [2]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calcitonin gene-related peptide 1 (CALCA) TTVSFJW CALCA_HUMAN Inhibitor [1]

References

1 Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26.
2 Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor. J Med Chem. 2008 Dec 25;51(24):7889-97.