Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPDVM8)

Drug Name
ABT-510 Drug Info
Synonyms N-Acetyl-N-methyl-glycyl-glycyl-L-valyl-D-alloisoleucyl-L-threonyl-L-norvalyl-L-isoleucyl-L-argininyl-L-proline N-ethylamide
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
Cross-matching ID
PubChem CID
6918562
CAS Number
CAS 251579-55-2
TTD Drug ID
DMPDVM8

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Thrombospondin-1 (THBS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CVX-045 DMCN9GX Solid tumour/cancer 2A00-2F9Z Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thrombospondin-1 (THBS1) TTKI0H1 TSP1_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT00602199) ABT-510 in Treating Patients With Metastatic Melanoma. U.S. National Institutes of Health.
2 A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma. Am J Clin Oncol. 2007 Jun;30(3):303-9.
3 Antitumor efficacy of a thrombospondin 1 mimetic CovX-body. Transl Oncol. 2011 Aug;4(4):249-57.