Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPZ97S)

Drug Name
Trofinetide Drug Info
Synonyms Glypromate analogs (oral, neuroprotection), Neuren; NNZ-2566 (oral, neurodegeneration/injury); NNZ-2566 (oral, neurodegeneration/injury), Neuren
Indication
Disease Entry ICD 11 Status REF
Rett syndrome LD90.4 Approved [1]
Fragile X syndrome LD55 Phase 2 [2]
Traumatic brain injury NA07.Z Phase 2 [3]
Type-1 diabetes 5A10 Phase 2 [4]
Cross-matching ID
PubChem CID
11318905
CAS Number
CAS 853400-76-7
TTD Drug ID
DMPZ97S

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neuropeptide receptor (NPR) TT9RTYG NOUNIPROTAC Modulator [4]

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 217026.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats. J Neuroinflammation. 2009 Aug 5;6:19.