Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQ95GE)

Drug Name

Phenylacetic acid Drug Info

Synonyms

.alpha.-Toluic acid; .omega.-Phenylacetic acid; 2-Phenylacetic acid; Acetic acid, phenyl-; Benzenacetic acid; Benzeneacetic acid; Benzylcarboxylic acid; Benzylformic acid; Kyselina fenyloctova; Kyselina fenyloctova [Czech]; PHENYL ACETIC ACID; PHENYL-ACETIC ACID; PHENYLACETIC ACID; Phenylacetic acid (natural); Phenylethanoic acid; Phenyllacetic acid; alpha-Toluic acid; omega-Phenylacetic acid; phenylacetate

Indication

Disease Entry	ICD 11	Status	REF
Hepatic encephalopathy	DB99.5	Approved	[1]
Ornithine transcarbamylase deficiency	5C50.AY	Approved	[2]

Cross-matching ID

PubChem CID: 999
ChEBI ID: CHEMBL1044
CAS Number: CAS 103-82-2
TTD Drug ID: DMQ95GE
VARIDT Drug ID: DR00333

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Monocarboxylate transporter 3 (SLC16A8)	DT39AOM	MOT3_HUMAN	Substrate	[3]

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References

1	Exposures of Phenylacetic Acid and Phenylacetylglutamine Across Different Subpopulations and Correlation with Adverse Events. Clin Pharmacokinet. 2021 Dec;60(12):1557-1567.
2	Glycerol Phenylbutyrate (Ravicti). Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Apr.
3	Immunohistochemical and functional characterization of peptide, organic cation, neutral and basic amino acid, and monocarboxylate drug transporters in human ocular tissues. Drug Metab Dispos. 2013 Feb;41(2):466-74.