Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQAIU1)

Drug Name
RGLS4326 Drug Info
Synonyms UNII-UCH3QQH1C0; UCH3QQH1C0; RGLS-4326; 2229964-07-0
Indication
Disease Entry ICD 11 Status REF
Autosomal dominant polycystic kidney disease GB81 Phase 1 [1]
Cross-matching ID
PubChem CID
154824286
CAS Number
CAS 2229964-07-0
TTD Drug ID
DMQAIU1

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
microRNA hsa-miR-17 (MIR17) TTMGJ19 NOUNIPROTAC Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04536688) A Study of RGLS4326 in Patients With Autosomal Dominant Polycystic Kidney Disease. U.S. National Institutes of Health.
2 Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease. Nat Commun. 2019 Sep 12;10(1):4148.