General Information of Drug (ID: DMQDA5W)

Drug Name
CDRI-85/92 Drug Info
Synonyms Proton pump inhibitor (gastric ulcer), CDRI
Indication
Disease Entry ICD 11 Status REF
Stomach ulcer DA60.Z Investigative [1]
Cross-matching ID
TTD Drug ID
DMQDA5W

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexlansoprazole DM1DBV5 Erosive esophagitis DA25.0 Approved [2]
Rabeprazole DMMZXIW Bacterial infection 1A00-1C4Z Approved [3]
AG-SPT201 DMJRQDG Ulcerative colitis DD71 Phase 3 [4]
API-023 DM6P93J Gastroesophageal reflux disease DA22.Z Phase 1 [1]
Saliphenylhalamide DMLMRGH Solid tumour/cancer 2A00-2F9Z Preclinical [1]
PA-10040 DMELTM2 Cardiovascular disease BA00-BE2Z Investigative [1]
CA-50040 DMCLN6M Colorectal cancer 2B91.Z Investigative [1]
ARH-1029 DM8NETP Helicobacter infection DA42-DA63 Investigative [1]
OPC-22575 DMO4WH9 Ulcerative colitis DD71 Investigative [1]
⏷ Show the Full List of 9 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Gastric H(+)/K(+) ATPase alpha (ATP4A) TTF1QVM ATP4A_HUMAN Inhibitor [1]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 849).
2 Clinical pipeline report, company report or official report of Takeda (2009).
3 Review article: rabeprazole's tolerability profile in clinical trials. Aliment Pharmacol Ther. 1999 Oct;13 Suppl 5:17-23.
4 Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole. J Gastroenterol Hepatol. 1999 Mar;14(3):251-7.