Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQHAIK)

Drug Name

PMID21627121C2 Drug Info

Synonyms

GTPL8149; BDBM50418829

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting NIMA-related kinase 2 (NEK2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID20936789C31	DMUGWO6	Discovery agent	N.A.	Investigative	[2]
GSK579289A	DMJXHU8	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Irreversible Nek2 kinase inhibitors with cellular activity. J Med Chem. 2011 Jun 23;54(12):4133-46.
2	Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization. J Med Chem. 2010 Nov 11;53(21):7682-98.
3	Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1694-7.