Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQX5UA)

Drug Name

FLX-787 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Amyotrophic lateral sclerosis	8B60.0	Phase 2	[1]
Multiple sclerosis	8A40	Phase 2	[2]
Muscle spasm	MB47.3	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Melanoma antigen gp75 (TYRP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Flanvotumab	DM2SALJ	Melanoma	2C30	Phase 1	[3]
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Drug(s) Targeting Transient receptor potential channel (TRP channel)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
HC-030031	DMOY2AI	Inflammation	1A00-CA43.1	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Melanoma antigen gp75 (TYRP1)	TTFRV98	TYRP1_HUMAN	Activator	[2]
Transient receptor potential channel (TRP channel)	TT79AOF	NOUNIPROTAC	Agonist	[1]

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	National Cancer Institute Drug Dictionary (drug id 675217).
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4211).