Details of the Drug-Related molecule(s) Interaction Atlas

US9475795, 89 Drug Info

CHEMBL3889563; SCHEMBL15549096; JDTHPTFPMSSAJL-UHFFFAOYSA-N; BDBM250610; US9475795, 89; 4-(4-Chloro-2-methoxybenzyl)-1-((3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl)piperidin-4-ol

Cross-matching ID

PubChem CID

72551112

TTD Drug ID

DMR6ODL

General Information of Drug (ID: DMR6ODL)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Prokineticin receptor-1 (PROKR1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9475795, 80	DM0ZDL3	N. A.	N. A.	Patented	[1]
ZINC19658740	DMLZDAK	N. A.	N. A.	Patented	[2]
US9475795, 19	DMGPDEF	N. A.	N. A.	Patented	[1]
triazine compound PC10	DMCLA2D	Discovery agent	N.A.	Investigative	[3]
IS1	DMNF70P	Discovery agent	N.A.	Investigative	[4]
IS20	DMQ5GA9	Discovery agent	N.A.	Investigative	[4]
------------------------------------------------------------------------------------


⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prokineticin receptor-1 (PROKR1)	TTB9CIL	PKR1_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases. US9475795.
2	Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases. US10167273.
3	Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain. J Nucl Med. 2011 Apr;52(4):600-7.
4	Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1. PLoS One. 2015 Apr 1;10(4):e0121027.