Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTMS3L)

Drug Name
Barucainide Drug Info
Synonyms
Barucainide; UNII-14NFL30YOH; 79784-22-8; 14NFL30YOH; Barucainidum; Barucainide [INN]; Barucainid; AC1Q1QCZ; AC1L3TX5; SCHEMBL2110723; CHEMBL2105905; DTXSID60229912; ZINC3643459; 4-Benzyl-1,3-dihydro-7-(4-(isopropylamino)butoxy)-6-methylfuro(3,4-c)pyridine; 4-[(4-benzyl-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-yl)oxy]-N-propan-2-ylbutan-1-amine
Indication
Disease Entry ICD 11 Status REF
Heart arrhythmia BC65 Terminated [1]
Cross-matching ID
PubChem CID
146795
CAS Number
CAS 79784-22-8
TTD Drug ID
DMTMS3L

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting E3 ubiquitin-protein ligase COP1 (RFWD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [3]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [3]
Propafenone DMPIBJK Tachyarrhythmias BC71 Approved [3]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [3]
Tocainide DMYNMDP Ventricular arrhythmias BC71 Approved [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
E3 ubiquitin-protein ligase COP1 (RFWD2) TT05DLS COP1_HUMAN Modulator [2]
Voltage-gated sodium channel (Nav) TTIG65Q NOUNIPROTAC Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000197)
2 Barucainide, a novel class Ib antiarrhythmic agent with a slow kinetic property: electrophysiologic observations in isolated canine and rabbit cardiac muscle. Am Heart J. 1990 May;119(5):1050-60.
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.