Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTV5NU)

Drug Name

PMID27998201-Compound-11 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Metastatic cancer	2D50-2E2Z	Patented	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Preclinical Drug(s)

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Drug(s) Targeting Cathepsin B (CTSB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID27998201-Compound-12	DM8QZNC	Bone cancer	2B5Z	Patented	[1]
PMID27998201-Compound-5	DMVZ0ND	Chronic obstructive pulmonary disease	CA22	Patented	[1]
PMID27998201-Compound-9	DM1JOZN	Rheumatoid arthritis	FA20	Patented	[1]
PMID27998201-Compound-17	DMAZVHJ	Hair loss	ED70	Patented	[1]
PMID27998201-Compound-2	DMMAE3C	Alzheimer disease	8A20	Patented	[1]
PMID27998201-Compound-22	DMS9QA7	Alzheimer disease	8A20	Patented	[1]
PMID27998201-Compound-13	DMZHIM8	Hepatic fibrosis	DB93.0	Patented	[1]
Dimethoxybenzylidene-2-thio-imidazole-4-one derivative 1	DMZ4B3W	Cerebral ischemia	8B11	Patented	[1]
PMID27998201-Compound-24	DM25BNZ	Glioma	2A00.0	Patented	[1]
L-006235-1	DMMEH12	Osteoarthritis	FA00-FA05	Preclinical	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656.
2	Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional se... J Med Chem. 2005 Dec 1;48(24):7535-43.