Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTZC5G)

Drug Name

Bezlotoxumab Drug Info

Synonyms

CDB1; Clostridium difficile toxin B monoclonal antibody; MBL-CDB1; MDX-1388; MK 6072; Zinplava

Indication

Disease Entry	ICD 11	Status	REF
C. difficile infection	1A04	Approved	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Clostridium difficile Toxin B (CD toxB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MK-3415A	DMGNHC2	Clostridium infection	1A04	Phase 3	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Clostridium difficile Toxin B (CD toxB)	TTQH65V	TOXB_CLODI	Modulator	[1]

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References

1	2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76.
2	ClinicalTrials.gov (NCT01513239) A Study of MK-6072 and MK-3415A in Participants Receiving Antibiotic Therapy for Clostridium Difficile Infection (MK-3415A-002). U.S. National Institutes of Health.