Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMU75ZX)

Drug Name
PMID25991433-Compound-J5 Drug Info
Cross-matching ID
PubChem CID
57340689
ChEBI ID
CHEBI:124926
TTD Drug ID
DMU75ZX

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Stress-activated protein kinase JNK3 (JNK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID25991433-Compound-A1 DM89LF0 N. A. N. A. Patented [1]
PMID25991433-Compound-F2 DM37VIQ N. A. N. A. Patented [1]
7-azaindole derivative 1 DMQL5B7 N. A. N. A. Patented [1]
7-azaindole derivative 5 DMV3H98 N. A. N. A. Patented [1]
PMID25991433-Compound-P6 DMNDVC9 N. A. N. A. Patented [1]
PMID25991433-Compound-J3 DM17P3F N. A. N. A. Patented [1]
PMID25991433-Compound-P1 DMD8AX6 N. A. N. A. Patented [1]
PMID25991433-Compound-O3 DMVOWS5 N. A. N. A. Patented [1]
PMID25991433-Compound-J2 DMZSOCK N. A. N. A. Patented [1]
7-azaindole derivative 3 DMQ7BV4 N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Stress-activated protein kinase JNK1 (JNK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
NKP-1339 DM5AWK1 Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
PMID25991433-Compound-A1 DM89LF0 N. A. N. A. Patented [1]
PMID25991433-Compound-F2 DM37VIQ N. A. N. A. Patented [1]
7-azaindole derivative 1 DMQL5B7 N. A. N. A. Patented [1]
7-azaindole derivative 5 DMV3H98 N. A. N. A. Patented [1]
PMID25991433-Compound-P6 DMNDVC9 N. A. N. A. Patented [1]
PMID25991433-Compound-J3 DM17P3F N. A. N. A. Patented [1]
PMID25991433-Compound-P1 DMD8AX6 N. A. N. A. Patented [1]
PMID25991433-Compound-O3 DMVOWS5 N. A. N. A. Patented [1]
PMID25991433-Compound-L1 DM2135Y N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Stress-activated protein kinase JNK2 (JNK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID25991433-Compound-A1 DM89LF0 N. A. N. A. Patented [1]
PMID25991433-Compound-F2 DM37VIQ N. A. N. A. Patented [1]
7-azaindole derivative 1 DMQL5B7 N. A. N. A. Patented [1]
7-azaindole derivative 5 DMV3H98 N. A. N. A. Patented [1]
PMID25991433-Compound-P6 DMNDVC9 N. A. N. A. Patented [1]
PMID25991433-Compound-J3 DM17P3F N. A. N. A. Patented [1]
PMID25991433-Compound-P1 DMD8AX6 N. A. N. A. Patented [1]
PMID25991433-Compound-O3 DMVOWS5 N. A. N. A. Patented [1]
PMID25991433-Compound-J2 DMZSOCK N. A. N. A. Patented [1]
7-azaindole derivative 3 DMQ7BV4 N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Stress-activated protein kinase JNK1 (JNK1) TT0K6EO MK08_HUMAN Inhibitor [1]
Stress-activated protein kinase JNK2 (JNK2) TTHS0U8 MK09_HUMAN Inhibitor [1]
Stress-activated protein kinase JNK3 (JNK3) TT056SO MK10_HUMAN Inhibitor [1]

References

1 c-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).Expert Opin Ther Pat. 2015;25(8):849-72.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1496).