Details of the Drug-Related molecule(s) Interaction Atlas

US9650366, 9 Drug Info

SCHEMBL17670002; OGVARLFWIBVKET-UHFFFAOYSA-N; BDBM308058; US9650366, 9; N-[3-({5-[2-(3-hydroxypropyl)-2H-tetrazol-5-yl]pyridin-3-yl}ethynyl)phenyl]-3-methyl-2-furamide

Cross-matching ID

PubChem CID

121268893

TTD Drug ID

DMUCIPE

General Information of Drug (ID: DMUCIPE)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Tyrosine-protein kinase EIF2AK2 (p68)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9650366, 12	DMR3Z49	N. A.	N. A.	Patented	[1]
US9650366, 2	DM9HZ03	N. A.	N. A.	Patented	[1]
NU6140	DMCUSG3	Discovery agent	N.A.	Investigative	[2]
ASN-11124542	DMFNZOI	Discovery agent	N.A.	Investigative	[3]
indirubin derivative E804	DMFP1C5	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosine-protein kinase EIF2AK2 (p68)	TTXEZJ4	E2AK2_HUMAN	Inhibitor	[1]

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References

1	Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors. US9650366.
2	Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.
3	Small molecule inhibitors of the RNA-dependent protein kinase. Biochem Biophys Res Commun. 2003 Aug 15;308(1):50-7.