Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUPCA6)

Drug Name

s-allylglycine Drug Info

Synonyms

L-Allylglycine; 16338-48-0; (S)-2-aminopent-4-enoic acid; H-Gly(Ally)-OH; (2S)-2-aminopent-4-enoic acid; (S)-(-)-2-Amino-4-pentenoic acid; (S)-2-Amino-4-pentenoic acid; L-alpha-Allyl-Gly; L-2-Amino-4-pentenoic acid; (S)-2-Amino-4- Pentenoic Acid; (S)-ALLYLGLYCINE; 3-VINYL-L-ALANINE; 4-Pentenoic acid, 2-amino-, (2S)-; (2S)-2-amino-4-pentenoic acid; (S)-2-Amino-pent-4-enoic acid; MFCD00002627; s-allylglycine; D-Allylglycine hydrochloride; (-)-Allylglycine; H-Gly(allyl)-OH; (S)-(-)-alpha-Allylglycine, 98%, 98% ee; C5H9NO2

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 167529
CAS Number: CAS 16338-48-0
TTD Drug ID: DMUPCA6

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Glutamate decarboxylase 2 (GAD2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Diamyd	DMOUGX1	Type-1 diabetes	5A10	Phase 3	[4]
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Drug(s) Targeting Glutamic acid decarboxylase 1 (GAD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AAV-GAD	DMOOY9W	Parkinson disease	8A00.0	Phase 2	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glutamate decarboxylase 2 (GAD2)	TT7UY6K	DCE2_HUMAN	Inhibitor	[2]
Glutamic acid decarboxylase 1 (GAD1)	TTKGEP3	DCE1_HUMAN	Inhibitor	[3]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5267).
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1273).
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1272).
4	Clinical pipeline report, company report or official report of Diamyd Medical.
5	Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet. 2007 Jun 23;369(9579):2097-105.