Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMV89B4)

Drug Name
YGRKKRRQRRR-KLSSIESDV Drug Info
Synonyms
UNII-D45TI2TWMA; D45TI2TWMA; 500992-11-0; L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L- glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-seryl-L-seryl-L-isoleucyl-L-alpha-glutamyl-L-seryl-L-alpha-aspartyl-L-valine; L-Valine, L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L- glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-seryl-L-seryl-L-isoleucyl-L-alpha-glutamyl-L-seryl-L-alpha-aspartyl-
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
91935893
TTD Drug ID
DMV89B4

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Presynaptic density protein 95 (DLG4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tat-NR2B9c DMD6AUX Cerebrovascular ischaemia 8B1Z Phase 3 [2]
2-Methyl-2,4-Pentanediol DMD45CU Discovery agent N.A. Investigative [3]
Guanosine-5'-Monophosphate DM3SLZK Discovery agent N.A. Investigative [3]
KSG-YEKLSSIESDV DMPLFRC Discovery agent N.A. Investigative [1]
N-(3,4-Difluorophenyl)propyl-ETAV DMF2D4O Discovery agent N.A. Investigative [1]
N-Propyl-ETAV DMUTDNV Discovery agent N.A. Investigative [1]
N-Phenylethyl-ETAV DM1VSO9 Discovery agent N.A. Investigative [1]
N-Cyclohexylmethyl-ETAV DMIC8Z6 Discovery agent N.A. Investigative [1]
FETAV DMO1N2T Discovery agent N.A. Investigative [1]
N-Butyl-ETAV DMY3HEF Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Presynaptic density protein 95 (DLG4) TT9PB26 DLG4_HUMAN Inhibitor [1]

References

1 Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. J Med Chem. 2008 Oct 23;51(20):6450-9.
2 Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature. 2012 Feb 29;483(7388):213-7.
3 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.