Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVHTQI)

Drug Name

CDE-5498 Drug Info

Synonyms

Dev-0304; Dev-0305; Kv4.3 voltage-dependent potassium channel antagonists (arrhythmia); Kv4.3 voltage-dependent potassium channel antagonists (arrhythmia), Devgen

Indication

Disease Entry	ICD 11	Status	REF
Heart arrhythmia	BC65	Terminated	[1]

Cross-matching ID

TTD Drug ID: DMVHTQI

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

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Drug(s) Targeting Voltage-gated potassium channel Kv4.3 (KCND3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sodium bicarbonate	DMMU6BJ	Metabolic acidosis	5C73	Approved	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Voltage-gated potassium channel Kv4.3 (KCND3)	TTPLQO0	KCND3_HUMAN	Antagonist	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020444)
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020444)
3	Management of cocaine-induced cardiac arrhythmias due to cardiac ion channel dysfunction. Clin Toxicol (Phila). 2009 Jan;47(1):14-23.