Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVL8PB)

Drug Name
IoGen Drug Info
Synonyms Oral iodine-based therapy (fibrocystic breast disease), Symbollon; Oral iodine-based therapy (fibrocystic breast disease), Symbollon/Gardant
Indication
Disease Entry ICD 11 Status REF
Pain MG30-MG3Z Discontinued in Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMVL8PB

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Estrogen receptor (ESR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [3]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [4]
Estrone DM5T6US Acne vulgaris ED80 Approved [4]
Estradiol Valerate DM8MC6O Hormone replacement therapy 8E01 Approved [5]
Estradiol Acetate DM07U2A Hormone replacement therapy 8E01 Approved [5]
Estradiol Cypionate DM27Z5T Hormone replacement therapy 8E01 Approved [5]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [6]
Raloxifene DMDKF3M Osteoporosis FB83.0 Approved [2]
Ospemifene DMC4GEI Dyspareunia GA12 Approved [7]
Toremifene DMQYUWG Breast cancer 2C60-2C65 Approved [8]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Estrogen receptor (ESR) TTZAYWL ESR1_HUMAN Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011554)
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 620).
3 Modulators of vascular sex hormone receptors and their effects in estrogen-deficiency states associated with menopause. Recent Pat Cardiovasc Drug Discov. 2008 Nov;3(3):165-86.
4 Reprint of Are all estrogens the same Maturitas. 2008 Sep-Oct;61(1-2):195-201.
5 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
6 17alpha-Ethinylestradiol hinders nucleotide excision repair in zebrafish liver cells. Aquat Toxicol. 2009 Dec 13;95(4):273-8.
7 Clinical pipeline report, company report or official report of Shionogi (2011).
8 Effect of selective estrogen receptor modulators on cell proliferation and estrogen receptor activities in normal human prostate stromal and epithe... Prostate Cancer Prostatic Dis. 2009;12(4):375-81.