Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVSTG7)

Drug Name
2-[(2,2-diphenylacetyl)amino]benzoic acid Drug Info
Synonyms
2-[(2,2-diphenylacetyl)amino]benzoic Acid; CHEMBL196755; 2-[(diphenylacetyl)amino]benzoic acid; Oprea1_593830; Oprea1_339985; MLS001143352; AC1N2C22; MolPort-001-015-645; HMS2781B19; ZINC3466236; BDBM50174204; STK004896; AKOS003244646; MCULE-3235692188; 2-(2,2-diphenylacetylamino)benzoic acid; SMR000473187
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
4044373
TTD Drug ID
DMVSTG7

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Dihydrodiol dehydrogenase type I (AKR1C3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flufenamic Acid DMC8VNH Dysmenorrhea GA34.3 Approved [2]
ASP-9521 DM8V0UL Prostate cancer 2C82.0 Phase 1/2 [3]
N-(benzimidazole/indole) benzoic acid derivative 2 DMOPUFM N. A. N. A. Patented [4]
N-(phenylamino)-benzoate derivative 1 DMNIWVG N. A. N. A. Patented [4]
Indomethacin analog 3 DM53JXE N. A. N. A. Patented [4]
Indomethacin analog 2 DMKFPJ7 N. A. N. A. Patented [4]
Beta-naphthylacetic acids derivative 1 DM5KTDY N. A. N. A. Patented [4]
Indomethacin analog 1 DM3E5V6 N. A. N. A. Patented [4]
N-(naphthylamino)-benzoate derivative 1 DM310ES N. A. N. A. Patented [4]
N-(benzimidazolylcarbonyl)-piperidine derivative 1 DM541QW N. A. N. A. Patented [4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dihydrodiol dehydrogenase type I (AKR1C3) TT5ZWB6 AK1C3_HUMAN Inhibitor [1]

References

1 Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of ant... Bioorg Med Chem Lett. 2005 Dec 1;15(23):5170-5.
2 Ouellet M, Percival MD: Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms. Biochem J. 1995 Feb 15;306 ( Pt 1):247-51.
3 Safety, tolerability and anti-tumour activity of the androgen biosynthesis inhibitor ASP9521 in patients with metastatic castration-resistant prostate cancer: multi-centre phase I/II study. Invest New Drugs. 2014 Oct;32(5):995-1004.
4 Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Dec;27(12):1329-1340.