Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMW5V4U)

Drug Name

Enfortumab vedotin Drug Info

Synonyms

Padcev

Indication

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Nectin cell adhesion molecule 4 (NECTIN4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Enfortumab	DMFS63G	Urothelial carcinoma	2C92.0	Approved	[4]
BT8009	DM1FJW6	Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[5]
ASG-22ME	DM0Z3JS	Solid tumour/cancer	2A00-2F9Z	Phase 1	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nectin cell adhesion molecule 4 (NECTIN4)	TTPO9EG	NECT4_HUMAN	Not Available	[3]

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References

1	FDA Approved Drug Products from FDA Official Website.
2	ClinicalTrials.gov (NCT03474107) An Open-Label, Randomized Phase 3 Study to Evaluate Enfortumab Vedotin vs Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301). U.S.National Institutes of Health.
3	Antibody-drug conjugates: Smart chemotherapy delivery across tumor histologies. CA Cancer J Clin. 2022 Mar;72(2):165-182.
4	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
5	Clinical pipeline report, company report or official report of Bicycle Therapeutics.
6	2011 Pipeline of Seattle Genetics.