Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXTV1B)

Drug Name

6-phenylpyridazin-3-yl thiophene-2-carboxylate Drug Info

Synonyms

CHEMBL1253380; AC1O4BXS; 6-phenylpyridazin-3-yl thiophene-2-carboxylate; MolPort-002-097-410; HMS1597J02; ZINC1059557; BDBM50326574; MCULE-6134548476; (6-phenylpyridazin-3-yl) thiophene-2-carboxylate

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6403448
TTD Drug ID: DMXTV1B

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting MIF messenger RNA (MIF mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 112690	DM6PO0N	Discovery agent	N.A.	Investigative	[2]
Ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate	DM7FPX8	Discovery agent	N.A.	Investigative	[3]
ISIS 112724	DMB2O1Y	Discovery agent	N.A.	Investigative	[2]
3-benzyl-6-methylbenzo[d]oxazol-2(3H)-one	DMGPKIY	Discovery agent	N.A.	Investigative	[4]
2-(4-hydroxystyryl)quinolin-8-ol	DM8GBH4	Discovery agent	N.A.	Investigative	[3]
7-hydroxy-3-phenyl-2H-chromen-2-one	DM2ZE8U	Discovery agent	N.A.	Investigative	[3]
3-benzyl-5-fluorobenzo[d]oxazol-2(3H)-one	DMZ85NC	Discovery agent	N.A.	Investigative	[4]
ISIS 112696	DMXZS4Y	Discovery agent	N.A.	Investigative	[2]
4-((pyridin-4-ylthio)methyl)benzene-1,2-diol	DM7X2AY	Discovery agent	N.A.	Investigative	[5]
3-acetyl-7-hydroxy-2H-chromen-2-one	DM01WBD	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
MIF messenger RNA (MIF mRNA)	TT6804T	MIF_HUMAN	Inhibitor	[1]

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References

1	An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity. Bioorg Med Chem. 2010 Jul 15;18(14):5425-40.
2	US patent application no. 6,268,151, Antisense modulation of macrophage migration inhibitory factor expression.
3	Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening. J Med Chem. 2009 Jan 22;52(2):416-24.
4	Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF). Bioorg Med Chem Lett. 2010 Oct 1;20(19):5811-4.
5	Classification of chemical compounds by protein-compound docking for use in designing a focused library. J Med Chem. 2006 Jan 26;49(2):523-33.