Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXV5PM)

Drug Name
EZN-3920 Drug Info
Synonyms SPC-3920; ERBB3 RNA inhibitor (cancer), Enzon/Santaris
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Cross-matching ID
TTD Drug ID
DMXV5PM

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ERBB3 messenger RNA (ERBB3 mRNA) TTSINU2 ERBB3_HUMAN Inhibitor [1]

References

1 Downregulation of HER3 by a novel antisense oligonucleotide, EZN-3920, improves the antitumor activity of EGFR and HER2 tyrosine kinase inhibitors in animal models. Mol Cancer Ther. 2013 Apr;12(4):427-37.