Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMY7W2U)

Drug Name
PMID12127536C20 Drug Info
Synonyms GTPL8650; BDBM50116264
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44310146
TTD Drug ID
DMY7W2U

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Granzyme B (GZMB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
VDA-1124 DMN62VE Aortic aneurysm BD50 Investigative [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Granzyme B (GZMB) TTKEPHX GRAB_HUMAN Inhibitor [1]

References

1 Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2197-200.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2369).