Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYS6MW)

Drug Name
GCS-100 Drug Info
Indication
Disease Entry ICD 11 Status REF
Chronic kidney disease GB61 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMYS6MW

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Galectin (LGALS) TTX1OI0 NOUNIPROTAC Modulator [2]

References

1 ClinicalTrials.gov (NCT01843790) A Phase 2a Study of Weekly Doses of GCS-100 in Patients With Chronic Kidney Disease. U.S. National Institutes of Health.
2 GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death. Blood. 2010 May 13;115(19):3939-48.