General Information of Drug (ID: DMYVJHN)

Drug Name
Trans-(1S(R),2S(R))-2-Hydroxycyclooctyl nitrate Drug Info
Synonyms CHEMBL556256; trans-(1S(R),2S(R))-2-Hydroxycyclooctyl nitrate; BDBM50293661
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
45273021
TTD Drug ID
DMYVJHN

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Patented Agent(s)
Investigative Drug(s)
Drug(s) Targeting Glutathione reductase (GR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Oxidized glutathione DM9EQC0 Breast cancer 2C60-2C65 Approved [2]
Golden phosphorous acetyletic compound 2 DMYJ15A N. A. N. A. Patented [3]
Terpyridineplatinum(II) complexe 3 DM54EFD N. A. N. A. Patented [3]
Terpyridineplatinum(II) complexe 4 DMOV86T N. A. N. A. Patented [3]
Golden phosphorous acetyletic compound 1 DMVAKUI N. A. N. A. Patented [3]
Acyl oxymethyl acrylamide ester derivative 1 DMXTUE1 N. A. N. A. Patented [3]
Nicotinamide-Adenine-Dinucleotide DM9LRKB N. A. N. A. Investigative [4]
Flavin-Adenine Dinucleotide DM5S4GK Discovery agent N.A. Investigative [4]
3-Sulfinoalanine DMILTRN N. A. N. A. Investigative [4]
1-(2'-chlorophenyl)penta-1,4-dien-3-one DMKTZSY Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glutathione reductase (GR) TTEP6RV GSHR_HUMAN Inhibitor [1]

References

1 In vitro inhibition of human erythrocyte glutathione reductase by some new organic nitrates. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3661-3.
2 The purification and properties of glutathione reductase from the cestode Moniezia expansa. Int J Biochem Cell Biol. 1995 Apr;27(4):393-401.
3 Thioredoxin reductase inhibitors: a patent review.Expert Opin Ther Pat. 2017 May;27(5):547-556.
4 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
5 Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate. J Med Chem. 2005 Nov 17;48(23):7400-10.