Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYX7NI)

Drug Name
Acetohydroxamic Acid Drug Info
Synonyms
AHA; Acethydroxamsaeure; Acethydroxamsaure; Acetohydroxamate; HAE; Lithostat; Acethydroxamic acid; Acethydroxamsaeure [German]; Acetohydroximic acid; Acetyl hydroxyamino; Acetylhydroxamic acid; Acide acetohydroxamique; Acide acetohydroxamique [French]; Acido acetohidroxamico; Acido acetohidroxamico [Spanish]; Acidum acetohydroxamicum; Acidum acetohydroxamicum [Latin]; Cetohyroxamic acid; Methylhydroxamic acid; SJX HLdmMAH; AHA (TN); Acetic acid, oxime; Acetohydroxamic acid [USAN:INN]; Lithostat (TN); N-Acetyl hydroxyacetamide; N-Acetylhydroxylamine; N-Hydroxyacetamide; N-hydroxyacetimidic acid; N-hydroxyethanimidic acid; S14-0751; Acetohydroxamic acid (USP/INN); Acetamide, N-hydroxy-(9CI)
Indication
Disease Entry ICD 11 Status REF
Urinary tract infection GC08 Approved [1]
Therapeutic Class
Antiinfective Agents
Cross-matching ID
PubChem CID
1990
ChEBI ID
CHEMBL27777
CAS Number
CAS 546-88-3
TTD Drug ID
DMYX7NI
ACDINA Drug ID
D00805

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial Urease (Bact ureC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
3-(4-bromobenzyl)-1,1-dimethylselenourea DMAKMIJ Discovery agent N.A. Investigative [3]
1-cyclohexyl-1-isopropyl-3,3-dimethylselenourea DMS10LE Discovery agent N.A. Investigative [3]
3-dodecyl-1,1-dimethylthiourea DMO5EBI Discovery agent N.A. Investigative [3]
N-glycylglycinehydroxamic acid DMPEZHC Discovery agent N.A. Investigative [4]
3-(4-bromophenyl)-1,1-dimethylthiourea DMXMZRE Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Urease (Bact ureC) TTAS2UO URE1_KLEAE Inhibitor [2]

References

1 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018749.
2 Enzymatic, immunological and phylogenetic characterization of Brucella suis urease. BMC Microbiol. 2008 Jul 19;8:121.
3 Facile one-pot synthesis of thio and selenourea derivatives: a new class of potent urease inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6387-91.
4 Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases. J Med Chem. 2008 Sep 25;51(18):5736-44.