Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZ2XAP)

Drug Name
LX-1031 Drug Info
Synonyms LG-103; LP-389924; LP-507518; LP-533401; LP-615819; TPH inhibitor (IBS), Lexicon; Tryptophan 5-hydroxylase inhibitor(IBS), Lexicon
Indication
Disease Entry ICD 11 Status REF
Irritable bowel syndrome DD91.0 Phase 2 [1]
Cross-matching ID
PubChem CID
23633604
CAS Number
CAS 945976-76-1
TTD Drug ID
DMZ2XAP

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tryptophan 5-hydroxylase (TPH) TT7ZK9C NOUNIPROTAC Inhibitor [2]

References

1 ClinicalTrials.gov (NCT00813098) Study of LX1031 in Subjects With Non-Constipating Irritable Bowel Syndrome. U.S. National Institutes of Health.
2 LX-1031, a tryptophan 5-hydroxylase inhibitor that reduces 5-HT levels for the potential treatment of irritable bowel syndrome. IDrugs. 2010 Dec;13(12):921-8.