Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZ30JT)

Drug Name

Oxantel pamoate Drug Info

Synonyms

Telopar; Oxantel embonate; CP-14445; Oxantel pamoate (USAN); Telopar (TN); CP-14445-16; Phenol, 3-(2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl), (E)-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (1:1) (salt); 4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with (E)-3-(2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl)phenol (1:1)

Indication

Disease Entry	ICD 11	Status	REF
Trichuris trichiura infection	1F6G	Approved	[1]

Therapeutic Class

Anthelmintics

Cross-matching ID

PubChem CID: 5281086
ChEBI ID: CHEBI:7821
CAS Number: CAS 68813-55-8
TTD Drug ID: DMZ30JT

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Bacterial Fumarate reductase flavoprotein (Bact frdA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Thiabendazole	DM7YCK3	Ascariasis	1F62	Approved	[1]
Morantel tartrate	DM560Y3	Mature gastrointestinal nematode infection	1F6Y	Approved	[1]
Flavin-Adenine Dinucleotide	DM5S4GK	Discovery agent	N.A.	Investigative	[2]
Heme	DMGC287	Discovery agent	N.A.	Investigative	[3]
Fumarate	DM9VLS2	Discovery agent	N.A.	Investigative	[2]
2,3-DIMETHYL-1,4-NAPHTHOQUINONE	DMGXVBA	Discovery agent	N.A.	Investigative	[3]
Citraconic acid	DMCIM9A	Discovery agent	N.A.	Investigative	[4]
2-[1-(4-CHLORO-PHENYL)-ETHYL]-4,6-DINITRO-PHENOL	DMUZDSC	Discovery agent	N.A.	Investigative	[3]
2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE	DMJ3ATL	Discovery agent	N.A.	Investigative	[3]
Malate Like Intermediate	DM4OQWZ	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Fumarate reductase flavoprotein (Bact frdA)	TTHDSE2	FRDA_HELPY	Inhibitor	[1]

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References

1	Fumarate reductase is essential for Helicobacter pylori colonization of the mouse stomach. Microb Pathog. 2000 Nov;29(5):279-87.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
4	DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.