Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZQ803)

Drug Name
NSC-745885 Drug Info
Synonyms
NSC-745885; AC1MYPDK; SCHEMBL1217478; CHEMBL594366; SJPXIVLTCBBWKT-UHFFFAOYSA-N; MolPort-002-321-063; ZINC4016501; STK368283; NSC745885; AKOS005445050; MCULE-4713643178; ST50889307; anthra[1,2-c]1,2,5-thiadiazole-6,11-dione; anthra[1,2-c][1,2,5]thiadiazole-6,11-dione; anthra [1,2-c]-1,2,5-thiadiazole-6,11-dione
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
3835463
TTD Drug ID
DMZQ803

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting TERT messenger RNA (TERT mRNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [2]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [2]
2,7-Bis(acetamido)anthraquinone DM2EPM4 Discovery agent N.A. Investigative [3]
2,7-Bis(cyclohexanecarbonamido)anthraquinone DMTPZ8D Discovery agent N.A. Investigative [3]
2,7-Bis[2-(isopropylamino)acetamido]anthraquinone DMRQGWX Discovery agent N.A. Investigative [3]
NSC-745884 DM8W0J3 Discovery agent N.A. Investigative [1]
2,7-Bis[3-(piperidino)propionamido]anthraquinone DMET693 Discovery agent N.A. Investigative [3]
2,7-Bis(cyclopropanecarbonamido)anthraquinone DMY3V2B Discovery agent N.A. Investigative [3]
2,7-Bis(phenylacetamido)anthraquinone DMEVIBT Discovery agent N.A. Investigative [3]
NSC-745887 DMG9BWY Discovery agent N.A. Investigative [1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TERT messenger RNA (TERT mRNA) TTQY2EJ TERT_HUMAN Inhibitor [1]

References

1 Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28.
2 Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.
3 Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86.