General Information of Drug (ID: DMZRPM5)

Drug Name
HT1042 Drug Info
Synonyms 5-(3-nitrophenyl)-1,3,4-oxathiazol-2-one; CHEMBL3265177; 23589-77-7; NSC294566; AC1L6WL8; GTPL8649; SCHEMBL1781484; DTXSID10315430; BDBM50010993
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
325597
CAS Number
CAS 23589-77-7
TTD Drug ID
DMZRPM5

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
M3258 DM6PI5B Multiple myeloma 2A83 Phase 1 [3]
Peptide analog 21 DMJDFS1 N. A. N. A. Patented [4]
Peptide analog 23 DMDU21R N. A. N. A. Patented [4]
Peptide analog 41 DM96KXE N. A. N. A. Patented [4]
PMID29865878-Compound-53 DM6JV1W N. A. N. A. Patented [4]
PMID29865878-Compound-55 DMY52ZB N. A. N. A. Patented [4]
PMID29865878-Compound-46 DMP3MXK N. A. N. A. Patented [4]
PMID29865878-Compound-48 DMVQTR2 N. A. N. A. Patented [4]
PMID29865878-Compound-51 DM0LXT2 N. A. N. A. Patented [4]
PMID29865878-Compound-49 DMK0GTV N. A. N. A. Patented [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proteasome beta-8 (PS beta-8) TTEAD9J PSB8_HUMAN Inhibitor [2]

References

1 Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nat Immunol. 2011 Dec 25;13(2):129-35.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2408).
3 Clinical pipeline report, company report or official report of EMD Serono.
4 A patent review of immunoproteasome inhibitors.Expert Opin Ther Pat. 2018 Jul;28(7):517-540.