Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM0D9YJ)

Drug Name
Dirithromycin Drug Info
Synonyms
Dirithromycine; Dirithromycinum; Diritromicina; Divitross; Dynabac; Noriclan; Valodin; Dirithromycine [French]; Dirithromycinum [Latin]; Diritromicina [Spanish]; LY 237216; AS-E 136; ASE-136; Dynabac (TN); LY-237216; Dirithromycin (USP/INN); Dirithromycin [USAN:BAN:INN]; (9S)-9-deoxo-11-deoxy-9,11-[imino[2-(2-methoxyethoxy)ethylidene]erythromycin
Therapeutic ClassAntibiotics
Cross-matching ID
PubChem CID
6473883
ChEBI ID
CHEMBL1237072
CAS Number
CAS 62013-04-1
TTD Drug ID
D06ZUP
VARIDT Drug ID
DR01366
INTEDE Drug ID
DR0516

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
IL-17 signaling pathway -1.97 3.47e-3 84/94 (89.36%) TRADD;MUC5B;TRAF3;...
NF-kappa B signaling pathway -1.99 5.21e-3 90/104 (86.54%) TNFSF11;TLR4;BCL2L1;...
Steroid biosynthesis -1.99 1.04e-2 19/20 (95%) LSS;TM7SF2;MSMO1;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H