Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM1794O)

Drug Name
Pyrethroids Drug Info
Synonyms
resmethrin; 10453-86-8; Benzofuroline; For-syn; Penncapthrin; Resmethrine; Benzyfuroline; Isathrine; Enforcer; Chryson; Synthrin; Pyresthrin; Premgard; Crossfire; Chrysron; Resmethrin [ANSI]; Resbuthrin; Caswell No. 083E; Bioresmethrine; SB Pennick 1382; Penick 1382; Resmetrina [Portuguese]; ARI-B; Resmethrine [ISO-French]; S.B. Penick 1382; d-trans-Resmethrin; 5-Benzylfurfuryl chrysanthemate; NRDC 104; Bioresmethrin (d trans isomer); CCRIS 2501; HSDB 1516; SBP-1382; OMS-1206; EINECS 233-940-7; FMC 17370; ENT 27474; NIA 17370
Cross-matching ID
PubChem CID
5053
ChEBI ID
CHEMBL8811
CAS Number
CAS 10453-86-8
TTD Drug ID
D09LEP
INTEDE Drug ID
DR1868

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Proximal tubule bicarbonate reclamation 2.08 0.00e+0 21/23 (91.3%) CA2;PCK2;ATP1A2;...
Mineral absorption 2.06 0.00e+0 48/60 (80%) MT1G;MT1E;MT1H;...
Amoebiasis 2.01 9.07e-3 99/102 (97.06%) COL4A5;PRKCA;ACTN1;...
Glycolysis / Gluconeogenesis 1.94 1.02e-2 56/67 (83.58%) FBP1;ENO2;PKM;...
Bile secretion 1.92 1.09e-2 68/90 (75.56%) CA2;ABCC3;ATP1A2;...
Proteasome 1.87 1.81e-2 44/46 (95.65%) PSMB5;PSME3;PSMB3;...
Endocrine and other factor-regulated calcium reabsorpti... 1.87 1.56e-2 49/53 (92.45%) PRKCA;GNAQ;ATP1A2;...
Phenylalanine metabolism 1.75 4.59e-2 14/17 (82.35%) GOT2;MAOA;PAH;...
Pancreatic secretion 1.74 4.39e-2 87/102 (85.29%) CA2;PRKCA;GNAQ;...
Fructose and mannose metabolism 1.74 4.22e-2 30/33 (90.91%) FBP1;PFKFB3;ALDOB;...
Gastric acid secretion 1.73 4.21e-2 63/76 (82.89%) CA2;PRKCA;GNAQ;...
×

Pharmacogenomic Perturbation Across Diseases and Tissues

Bone
Osteosarcoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
U-2 OS CVCL_0042 Homo sapiens 10uM 6H
Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H, 24H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H, 24H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Non-small cell lung carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HCC515 CVCL_5134 Homo sapiens 10uM 6H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H, 24H