Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM1XHYJ)

Drug Name
Etidronic acid Drug Info
Synonyms
EHDP; Etidronate; Etidronsaeure; HEDP; Osteoscan; Acetodiphosphonic acid; Acide etidronique; Acido etidronico; Acidumetidronicum; Didronel IV; Etidronic acid monohydrate; Hydroxyethanediphosphonic acid; Oxyethylidenediphosphonic acid; Turpinal SL; Dequest2010; Dequest 2015; Dequest Z 010; Ferrofos 510; RP 61; Acide etidronique [INN-French]; Acido etidronico [INN-Spanish]; Acidum etidronicum [INN-Latin]; Diphosphonate (base); Etidronic acid (USAN/INN); Etidronic acid [USAN:INN:BAN]; Hydroxyethane-1,1-diphosphonic acid; Ethane-1-hydroxy-1,1-bisphosphonate; Ethane-1-hydroxy-1,1-bisphosphonic acid; Ethane-1-hydroxy-1,1-diphosphonate; Ethane-1-hydroxy-1,1-diphosphonic acid; Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester; (1-Hydroxyethylene)diphosphonic acid; (1-Hydroxyethylidene)bis(phosphonic acid); (1-Hydroxyethylidene)bisphosphonic acid; (1-Hydroxyethylidene)diphoshonic acid; (1-Hydroxyethylidene)diphosphonic acid; (1-hydroxy-1-phosphonoethyl)phosphonic acid; (1-hydroxyethane-1,1-diyl)bis(phosphonic acid); (Hydroxyethylidene)diphosphonic acid; 1,1,1-Ethanetriol diphosphonate; 1-HYDROXY-1,1-DIPHOSPHONOETHANE; 1-Hydroxyethane-1,1,-diphosphonic acid; 1-Hydroxyethane-1,1-bisphosphonic acid; 1-Hydroxyethane-1,1-diphosphonate; 1-Hydroxyethane-1,1-diphosphonic acid; 1-Hydroxyethanediphosphonic acid; 1-Hydroxyethylidene 1,1-diphosphonic acid; 1-Hydroxyethylidene-1,1-biphosphonate; 1-Hydroxyethylidene-1,1-bisphosphonate; 1-Hydroxyethylidene-1,1-diphosphonic acid; 1-Hydroxyethylidenediphosphonic acid; 1000SL
Therapeutic ClassBone Density Conservation Agents
Cross-matching ID
PubChem CID
3305
ChEBI ID
CHEMBL871
CAS Number
CAS 2809-21-4
TTD Drug ID
D00NNC
ACDINA Drug ID
D00256

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Pyrimidine metabolism 2.05 0.00e+0 40/56 (71.43%) CANT1;DCTD;DCK;...
Asthma -1.78 3.18e-2 25/31 (80.65%) IL5;EPX;HLA-DRB1;...
Cholesterol metabolism -1.79 2.94e-2 44/50 (88%) LCAT;APOA1;APOC2;...
Intestinal immune network for IgA production -1.83 2.60e-2 38/48 (79.17%) ITGB7;IL5;HLA-DRB1;...
PPAR signaling pathway -1.90 1.39e-2 66/74 (89.19%) APOC3;HMGCS2;SLC27A6;...
Mineral absorption -1.94 9.28e-3 48/60 (80%) FTL;SLC26A3;MT1F;...
Systemic lupus erythematosus -2.08 4.64e-3 45/135 (33.33%) TRIM21;C9;ACTN1;...
Staphylococcus aureus infection -2.13 9.28e-3 72/95 (75.79%) MBL2;PLG;HLA-DRB1;...
×

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Liver
Hepatocellular carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HuH-7 CVCL_0336 Homo sapiens 15uM 72H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H