| Systemic lupus erythematosus |
1.75 |
2.17e-1 |
45/135 (33.33%) |
C3;CTSG;ELANE;...
|
| Fc epsilon RI signaling pathway |
1.72 |
1.38e-1 |
57/68 (83.82%) |
ALOX5AP;PRKCA;ALOX5;...
|
| DNA replication |
1.63 |
2.62e-1 |
34/36 (94.44%) |
RFC2;PCNA;POLE3;...
|
| Hedgehog signaling pathway |
1.59 |
3.03e-1 |
43/56 (76.79%) |
PRKACB;CCND2;SCUBE2;...
|
| Asthma |
1.54 |
3.66e-1 |
25/31 (80.65%) |
FCER1G;FCER1A;PRG2;...
|
| RNA degradation |
1.52 |
3.67e-1 |
53/79 (67.09%) |
CNOT7;ENO3;TOB1;...
|
| Ribosome biogenesis in eukaryotes |
1.50 |
3.55e-1 |
52/108 (48.15%) |
NVL;NOP56;NXF3;...
|
| Cortisol synthesis and secretion |
1.49 |
3.41e-1 |
58/65 (89.23%) |
PRKACB;ADCY2;AGT;...
|
| Terpenoid backbone biosynthesis |
1.49 |
3.03e-1 |
18/22 (81.82%) |
HMGCS1;HMGCS2;PCYOX1;...
|
| GnRH signaling pathway |
1.49 |
2.83e-1 |
80/93 (86.02%) |
PRKACB;SRC;ADCY2;...
|
| Nicotinate and nicotinamide metabolism |
1.49 |
2.60e-1 |
25/35 (71.43%) |
QPRT;AOX1;ENPP1;...
|
| Aldosterone synthesis and secretion |
1.47 |
2.66e-1 |
85/98 (86.73%) |
PRKACB;ADCY2;ATP2B4;...
|
| Phototransduction |
1.45 |
2.84e-1 |
21/29 (72.41%) |
CALML5;CALML3;CNGA1;...
|
| Ovarian steroidogenesis |
1.44 |
3.05e-1 |
41/51 (80.39%) |
PRKACB;ADCY2;CYP17A1;...
|
| Pyrimidine metabolism |
1.39 |
4.12e-1 |
40/56 (71.43%) |
ENPP1;CTPS1;NME6;...
|
| C-type lectin receptor signaling pathway |
1.36 |
4.55e-1 |
93/104 (89.42%) |
NFATC3;SRC;PYCARD;...
|
| Salivary secretion |
1.35 |
4.54e-1 |
76/93 (81.72%) |
PRKACB;ADCY2;ATP2B4;...
|
| Butanoate metabolism |
1.34 |
4.72e-1 |
23/28 (82.14%) |
HMGCS1;ABAT;HMGCS2;...
|
| Starch and sucrose metabolism |
1.33 |
4.54e-1 |
25/36 (69.44%) |
GBE1;ENPP1;GYG1;...
|
| Calcium signaling pathway |
1.32 |
4.70e-1 |
213/240 (88.75%) |
PRKACB;ASPH;ADCY2;...
|
| Inflammatory mediator regulation of TRP channels |
1.32 |
4.62e-1 |
82/98 (83.67%) |
PRKACB;SRC;ADCY2;...
|
| Histidine metabolism |
1.29 |
5.14e-1 |
16/22 (72.73%) |
HAL;HNMT;HDC;...
|
| GnRH secretion |
1.29 |
5.19e-1 |
60/64 (93.75%) |
KCNN2;PRKCA;CGA;...
|
| Synthesis and degradation of ketone bodies |
1.28 |
5.20e-1 |
9/10 (90%) |
HMGCS1;HMGCS2
|
| Endocrine and other factor-regulated calcium reabsorpti... |
1.26 |
5.53e-1 |
49/53 (92.45%) |
PRKACB;ATP2B4;PRKCA;...
|
| RNA polymerase |
1.24 |
5.88e-1 |
23/31 (74.19%) |
POLR3G;POLR2I;POLR1C;...
|
| Homologous recombination |
1.23 |
6.05e-1 |
35/41 (85.37%) |
BARD1;NBN;RAD54B;...
|
| Wnt signaling pathway |
1.19 |
6.23e-1 |
124/166 (74.7%) |
PRKACB;NFATC3;SERPINF1;...
|
| Renin secretion |
1.19 |
6.08e-1 |
61/69 (88.41%) |
PRKACB;CALML5;AGT;...
|
| Prolactin signaling pathway |
1.19 |
6.07e-1 |
66/70 (94.29%) |
SRC;CCND2;CYP17A1;...
|
| Parathyroid hormone synthesis, secretion and action |
-1.41 |
2.22e-1 |
98/106 (92.45%) |
ADCY6;VDR;JUND;...
|
| Porphyrin and chlorophyll metabolism |
-1.45 |
1.78e-1 |
23/43 (53.49%) |
HMOX1
|
| Non-alcoholic fatty liver disease |
-1.45 |
1.83e-1 |
126/155 (81.29%) |
CEBPA;CASP3;COX6A2;...
|
| Gastric cancer |
-1.46 |
1.88e-1 |
122/149 (81.88%) |
FGFR2;ABCB1;E2F2;...
|
| Nicotine addiction |
-1.46 |
1.85e-1 |
32/40 (80%) |
GABRA1;GABRA5;GRIA2;...
|
| NF-kappa B signaling pathway |
-1.47 |
1.80e-1 |
90/104 (86.54%) |
PLCG2;MYD88;BIRC3;...
|
| Oxidative phosphorylation |
-1.48 |
1.76e-1 |
93/133 (69.92%) |
NDUFA8;COX7A2;ATP6V1A;...
|
| Protein processing in endoplasmic reticulum |
-1.49 |
1.67e-1 |
127/171 (74.27%) |
LMAN1;DDOST;SKP1;...
|
| Glycerolipid metabolism |
-1.49 |
1.66e-1 |
44/61 (72.13%) |
PNLIPRP2;ALDH3A2;MOGAT2;...
|
| Adipocytokine signaling pathway |
-1.49 |
1.72e-1 |
64/69 (92.75%) |
ACACB;PRKAG2;RELA;...
|
| Ferroptosis |
-1.50 |
1.67e-1 |
36/41 (87.8%) |
SLC3A2;SLC7A11;MAP1LC3B;...
|
| FoxO signaling pathway |
-1.51 |
1.71e-1 |
118/131 (90.08%) |
MAPK11;PCK1;INSR;...
|
| Adherens junction |
-1.51 |
1.80e-1 |
63/71 (88.73%) |
MAP3K7;AFDN;MAPK3;...
|
| Sulfur relay system |
-1.52 |
1.77e-1 |
5/8 (62.5%) |
TST;MPST
|
| Collecting duct acid secretion |
-1.55 |
1.58e-1 |
22/27 (81.48%) |
ATP6V1D;ATP6V1A;ATP6V0E2;...
|
| Chronic myeloid leukemia |
-1.55 |
1.67e-1 |
72/76 (94.74%) |
ABL1;RB1;STAT5A;...
|
| Transcriptional misregulation in cancer |
-1.56 |
1.67e-1 |
158/192 (82.29%) |
ITGB7;TFE3;LDB1;...
|
| Ether lipid metabolism |
-1.57 |
1.74e-1 |
32/49 (65.31%) |
PLD1;PLA2G6;PLA2G1B;...
|
| Mitophagy |
-1.57 |
1.89e-1 |
56/68 (82.35%) |
PINK1;SQSTM1;RELA;...
|
| Glutathione metabolism |
-1.58 |
1.75e-1 |
43/57 (75.44%) |
GSTA1;GSTK1;ODC1;...
|
| Glyoxylate and dicarboxylate metabolism |
-1.59 |
1.89e-1 |
23/30 (76.67%) |
MDH1;ACO1;CAT;...
|
| Pyruvate metabolism |
-1.60 |
1.83e-1 |
41/47 (87.23%) |
DLD;DLAT;ACACB;...
|
| Hepatocellular carcinoma |
-1.62 |
1.63e-1 |
135/168 (80.36%) |
E2F2;TXNRD1;FZD4;...
|
| Metabolism of xenobiotics by cytochrome P450 |
-1.63 |
1.73e-1 |
49/77 (63.64%) |
CYP2E1;GSTA1;GSTK1;...
|
| Thyroid cancer |
-1.66 |
1.40e-1 |
36/37 (97.3%) |
CCDC6;BAK1;DDB2;...
|
| Retinol metabolism |
-1.71 |
1.04e-1 |
41/68 (60.29%) |
HSD17B6;RDH5;RDH11;...
|
| Fluid shear stress and atherosclerosis |
-1.72 |
1.30e-1 |
123/139 (88.49%) |
GSTM1;MEF2A;ACVR1;...
|
| TNF signaling pathway |
-1.72 |
1.61e-1 |
103/112 (91.96%) |
TRAF1;IL15;MAPK11;...
|
| Sulfur metabolism |
-1.79 |
1.15e-1 |
9/10 (90%) |
PAPSS1;TST;MPST;...
|
| Citrate cycle (TCA cycle) |
-1.86 |
1.15e-1 |
30/30 (100%) |
ACLY;OGDHL;OGDH;...
|
