Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM20VMW)

Drug Name
Ethylestrenol Drug Info
Synonyms Maxibolin
Cross-matching ID
PubChem CID
13765
ChEBI ID
CHEMBL1200623
CAS Number
CAS 965-90-2
TTD Drug ID
D0SC8F

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Folate biosynthesis 2.00 2.09e-2 23/26 (88.46%) AKR1B1;SPR;QDPR;...
Nitrogen metabolism 1.91 3.13e-2 16/17 (94.12%) CA2;CA12;CA9;...
IL-17 signaling pathway 1.85 2.09e-2 84/94 (89.36%) S100A8;CXCL1;CXCL5;...
Histidine metabolism 1.79 3.66e-2 16/22 (72.73%) ALDH9A1;ASPA;ALDH7A1;...
Ferroptosis 1.79 3.13e-2 36/41 (87.8%) TFRC;PRNP;TF;...
Staphylococcus aureus infection 1.78 3.31e-2 72/95 (75.79%) KRT17;KRT19;CFD;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H