| Type I diabetes mellitus |
1.64 |
3.41e-1 |
38/43 (88.37%) |
PTPRN2;HLA-E;PRF1;...
|
| Complement and coagulation cascades |
1.61 |
3.54e-1 |
76/85 (89.41%) |
C5AR1;F13A1;C7;...
|
| Bile secretion |
1.60 |
3.02e-1 |
68/90 (75.56%) |
GNAS;ATP1A2;ABCB1;...
|
| Long-term depression |
1.58 |
2.79e-1 |
55/60 (91.67%) |
GNAS;LYN;GUCY1A1;...
|
| Glutamatergic synapse |
1.56 |
3.00e-1 |
97/114 (85.09%) |
GNAS;GNG7;PPP3CA;...
|
| Progesterone-mediated oocyte maturation |
1.55 |
2.74e-1 |
75/100 (75%) |
RPS6KA1;PLK1;MAPK10;...
|
| cGMP-PKG signaling pathway |
1.55 |
2.51e-1 |
145/167 (86.83%) |
ATP1A2;EDNRB;PPP3CA;...
|
| Vascular smooth muscle contraction |
1.52 |
2.82e-1 |
113/133 (84.96%) |
GNAS;GUCY1A1;MYH10;...
|
| Allograft rejection |
1.50 |
2.92e-1 |
32/38 (84.21%) |
HLA-E;PRF1;HLA-B;...
|
| Circadian entrainment |
1.50 |
2.72e-1 |
85/97 (87.63%) |
GNAS;GNG7;GUCY1A1;...
|
| cAMP signaling pathway |
1.49 |
2.68e-1 |
188/216 (87.04%) |
NPY1R;GNAS;OXTR;...
|
| Insulin secretion |
1.49 |
2.52e-1 |
75/86 (87.21%) |
GNAS;ATP1A2;RAPGEF4;...
|
| Graft-versus-host disease |
1.47 |
2.70e-1 |
32/42 (76.19%) |
HLA-E;PRF1;HLA-B;...
|
| Dilated cardiomyopathy |
1.46 |
2.79e-1 |
86/96 (89.58%) |
GNAS;DMD;PLN;...
|
| Oocyte meiosis |
1.46 |
2.63e-1 |
90/129 (69.77%) |
RPS6KA1;PLK1;PPP3CA;...
|
| Amoebiasis |
1.45 |
2.70e-1 |
99/102 (97.06%) |
GNAS;COL4A5;CXCL8;...
|
| Long-term potentiation |
1.45 |
2.65e-1 |
61/67 (91.04%) |
RPS6KA1;PPP3CA;PPP1R1A;...
|
| Calcium signaling pathway |
1.44 |
2.75e-1 |
213/240 (88.75%) |
MCOLN1;GNAS;OXTR;...
|
| Dopaminergic synapse |
1.43 |
2.77e-1 |
115/132 (87.12%) |
GNAS;GNG7;PPP3CA;...
|
| Adrenergic signaling in cardiomyocytes |
1.43 |
2.75e-1 |
130/150 (86.67%) |
GNAS;ATP1A2;PPP2R2B;...
|
| Leukocyte transendothelial migration |
1.42 |
2.71e-1 |
90/114 (78.95%) |
CDH5;CXCL12;CTNNA2;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
1.38 |
3.54e-1 |
49/53 (92.45%) |
GNAS;ATP1A2;AP2M1;...
|
| Various types of N-glycan biosynthesis |
1.38 |
3.39e-1 |
26/39 (66.67%) |
MGAT1;MGAT4A;MAN1A1;...
|
| Cardiac muscle contraction |
1.37 |
3.55e-1 |
64/87 (73.56%) |
ATP1A2;ASPH;CACNB2;...
|
| Cell adhesion molecules |
1.36 |
3.59e-1 |
118/148 (79.73%) |
CDH5;CDH2;SDC2;...
|
| Ovarian steroidogenesis |
1.33 |
3.78e-1 |
41/51 (80.39%) |
GNAS;ALOX5;CYP1B1;...
|
| Fc gamma R-mediated phagocytosis |
1.33 |
3.69e-1 |
79/97 (81.44%) |
LYN;MARCKS;FCGR3B;...
|
| N-Glycan biosynthesis |
1.32 |
3.76e-1 |
38/50 (76%) |
ST6GAL1;MGAT1;MGAT4A;...
|
| Primary bile acid biosynthesis |
1.32 |
3.65e-1 |
15/17 (88.24%) |
CYP27A1;CYP7A1;BAAT;...
|
| PPAR signaling pathway |
1.30 |
3.77e-1 |
66/74 (89.19%) |
SORBS1;FABP7;FABP5;...
|
| beta-Alanine metabolism |
-1.36 |
2.38e-1 |
25/30 (83.33%) |
AOC2;DPYD;ALDH3B1;...
|
| Glyoxylate and dicarboxylate metabolism |
-1.37 |
2.30e-1 |
23/30 (76.67%) |
HYI;MMUT;CAT;...
|
| Fluid shear stress and atherosclerosis |
-1.37 |
2.35e-1 |
123/139 (88.49%) |
IL1A;GSTO1;ACVR2B;...
|
| Toll-like receptor signaling pathway |
-1.38 |
2.27e-1 |
94/104 (90.38%) |
MAP3K7;IFNAR1;LY96;...
|
| Mitophagy |
-1.39 |
2.31e-1 |
56/68 (82.35%) |
TBC1D15;CSNK2A1;JUN;...
|
| Protein digestion and absorption |
-1.39 |
2.33e-1 |
78/103 (75.73%) |
PRSS3;COL1A1;SLC36A1;...
|
| TNF signaling pathway |
-1.40 |
2.25e-1 |
103/112 (91.96%) |
FADD;ATF4;MAPK1;...
|
| Arachidonic acid metabolism |
-1.41 |
2.06e-1 |
48/61 (78.69%) |
ALOX12;PLA2G4A;PTGS2;...
|
| Signaling pathways regulating pluripotency of stem cell... |
-1.41 |
2.15e-1 |
110/143 (76.92%) |
FGFR2;SMAD5;PCGF1;...
|
| Bladder cancer |
-1.41 |
2.23e-1 |
40/41 (97.56%) |
HBEGF;KRAS;MYC;...
|
| Riboflavin metabolism |
-1.42 |
2.32e-1 |
7/8 (87.5%) |
ACP1;BLVRB;ACP2;...
|
| Pantothenate and CoA biosynthesis |
-1.43 |
2.20e-1 |
14/21 (66.67%) |
DPYD;BCAT1;ALDH1B1;...
|
| Estrogen signaling pathway |
-1.43 |
2.25e-1 |
119/137 (86.86%) |
KRT33B;KRT38;GNAI1;...
|
| Neomycin, kanamycin and gentamicin biosynthesis |
-1.45 |
2.15e-1 |
5/5 (100%) |
HK3;HK2
|
| Glycosaminoglycan degradation |
-1.47 |
1.94e-1 |
19/19 (100%) |
HPSE2;HYAL1;ARSB;...
|
| Rheumatoid arthritis |
-1.47 |
1.99e-1 |
78/93 (83.87%) |
ATP6V0A1;ATP6V0A4;IL1A;...
|
| Oxidative phosphorylation |
-1.49 |
1.94e-1 |
93/133 (69.92%) |
ATP6V1E1;COX15;PPA2;...
|
| Fructose and mannose metabolism |
-1.49 |
1.97e-1 |
30/33 (90.91%) |
HK3;HK2;PMM1;...
|
| Glycolysis / Gluconeogenesis |
-1.50 |
2.06e-1 |
56/67 (83.58%) |
PCK1;ENO1;ENO3;...
|
| Arginine and proline metabolism |
-1.55 |
1.44e-1 |
39/50 (78%) |
OAT;GOT2;GOT1;...
|
| Nitrogen metabolism |
-1.58 |
1.29e-1 |
16/17 (94.12%) |
CA6;GLUD2;GLUD1;...
|
| TGF-beta signaling pathway |
-1.59 |
1.26e-1 |
81/94 (86.17%) |
E2F5;PPP2R1B;ACVR2B;...
|
| Glutathione metabolism |
-1.59 |
1.42e-1 |
43/57 (75.44%) |
GSR;PGD;GSTM3;...
|
| Lysosome |
-1.60 |
1.54e-1 |
115/128 (89.84%) |
ARSB;CTSV;GALNS;...
|
| alpha-Linolenic acid metabolism |
-1.61 |
1.70e-1 |
17/25 (68%) |
PLA2G4A;FADS2;PLA2G2D;...
|
| Nicotinate and nicotinamide metabolism |
-1.63 |
1.56e-1 |
25/35 (71.43%) |
SIRT2;NT5C2;SIRT7;...
|
| Selenocompound metabolism |
-1.65 |
1.56e-1 |
11/17 (64.71%) |
SCLY;KYAT3;CTH;...
|
| Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
-1.71 |
1.39e-1 |
20/26 (76.92%) |
PIGN;MPPE1;PIGZ;...
|
| Histidine metabolism |
-1.77 |
7.43e-2 |
16/22 (72.73%) |
ALDH3B1;HDC;HNMT;...
|
| Sulfur metabolism |
-1.84 |
6.50e-2 |
9/10 (90%) |
SQOR;SELENBP1;TST;...
|
