Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM2U4XQ)

• Drug Name: ALCURONIUM Drug Info
• Synonyms: Alcuronium
• Cross-matching ID:
  PubChem CID: 21158560
  ChEBI ID: CHEMBL55313
  CAS Number: CAS 23214-96-2
  TTD Drug ID: D0L1OY

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Human immunodeficiency virus 1 infection	-1.75	4.00e-2	189/212 (89.15%)	BCL2;RELA;TAPBP;...
Epstein-Barr virus infection	-1.77	3.25e-2	189/202 (93.56%)	BCL2;RELA;TAPBP;...
IL-17 signaling pathway	-1.79	2.69e-2	84/94 (89.36%)	NFKBIA;MAPK13;MAPK10;...
Type I diabetes mellitus	-1.81	2.64e-2	38/43 (88.37%)	FAS;GAD1;HLA-F;...
Natural killer cell mediated cytotoxicity	-1.87	7.70e-3	99/131 (75.57%)	SH2D1A;LCK;KIR3DL1;...
Allograft rejection	-1.94	3.08e-3	32/38 (84.21%)	FAS;HLA-F;CD80;...
Herpes simplex virus 1 infection	-1.96	3.85e-3	165/498 (33.13%)	BCL2;RELA;PILRA;...
Rheumatoid arthritis	-2.05	5.13e-3	78/93 (83.87%)	ATP6AP1;IL1A;ATP6V1E1;...
Antigen processing and presentation	-2.19	0.00e+0	60/78 (76.92%)	KIR3DL1;TAPBP;KIR2DL3;...
Graft-versus-host disease	-2.24	0.00e+0	32/42 (76.19%)	KIR3DL1;KIR2DL3;FAS;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Hide ▲