Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM2ZLD7)

Drug Name
bisphenol A Drug Info
Synonyms BPA
Cross-matching ID
PubChem CID
6623
ChEBI ID
CHEMBL418971
CAS Number
CAS 80-05-7
TTD Drug ID
D02RQP
INTEDE Drug ID
DR1984

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Malaria 2.13 0.00e+0 44/50 (88%) IL1B;MET;COMP;...
Mineral absorption 2.11 0.00e+0 48/60 (80%) MT1F;SLC39A4;MT1G;...
ECM-receptor interaction 1.98 0.00e+0 80/88 (90.91%) LAMC2;COMP;ITGA10;...
Nicotinate and nicotinamide metabolism 1.91 2.35e-3 25/35 (71.43%) SIRT3;NNMT;NT5E;...
Bladder cancer 1.84 1.69e-2 40/41 (97.56%) HBEGF;VEGFA;CXCL8;...
Rheumatoid arthritis 1.84 1.57e-2 78/93 (83.87%) CXCL5;IL1B;HLA-DQB1;...
TGF-beta signaling pathway 1.73 3.36e-2 81/94 (86.17%) INHBA;ID4;FST;...
Amino sugar and nucleotide sugar metabolism 1.72 3.52e-2 38/48 (79.17%) GFPT1;GMDS;UAP1;...
Salivary secretion -1.76 4.82e-2 76/93 (81.72%) CHRM3;GUCY1A1;DMBT1;...
Aldosterone-regulated sodium reabsorption -1.80 2.50e-2 34/37 (91.89%) PRKCA;ATP1A2;KRAS;...
Steroid biosynthesis -2.05 0.00e+0 19/20 (95%) FDFT1;LBR;SC5D;...
Terpenoid backbone biosynthesis -2.05 0.00e+0 18/22 (81.82%) MVD;MVK;PCYOX1;...
×

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H
Breast epithelium
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF-10A CVCL_0598 Homo sapiens 12uM - 100uM 48H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H, 24H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 0.08uM - 100uM 3H, 24H, 48H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 0.08uM - 20uM 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H