Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM3JFIH)

• Drug Name: Vancomycin Drug Info
• Synonyms: Vancomycin (oral, MRSA), AuricX; Vancomycin (oral/pill, MSRA); Vancomycin (oral/pill, MSRA), AuricX/SRI International
• Cross-matching ID:
  PubChem CID: 14969
  ChEBI ID: CHEMBL262777
  CAS Number: CAS 1404-90-6
  TTD Drug ID: D0B1IV

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Fructose and mannose metabolism	2.01	8.60e-3	30/33 (90.91%)	AKR1B10;PFKFB3;HK2;...
Galactose metabolism	1.89	2.15e-2	26/31 (83.87%)	AKR1B10;HK2;HKDC1;...
Porphyrin and chlorophyll metabolism	1.86	2.58e-2	23/43 (53.49%)	HMBS;CP;ALAS2;...
Thyroid cancer	1.77	3.44e-2	36/37 (97.3%)	RXRA;CDKN1A;TP53;...
Tryptophan metabolism	-2.01	0.00e+0	35/42 (83.33%)	DLST;KYNU;ALDH1B1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Hide ▲