Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM4UXT1)

• Drug Name: tyramine Drug Info
• Synonyms: Tyramine; 4-(2-Aminoethyl)phenol; 51-67-2; 4-Hydroxyphenethylamine; p-Tyramine; 2-(4-Hydroxyphenyl)ethylamine; Uteramine; Tyramin; Tyrosamine; Tocosine; 4-Hydroxyphenylethylamine; Systogene; Phenol, 4-(2-aminoethyl)-; p-Hydroxyphenethylamine; Tenosin-wirkstoff; p-Hydroxyphenylethylamine; p-(2-Aminoethyl)phenol; 2-(p-Hydroxyphenyl)ethylamine; Phenethylamine, p-hydroxy-; p-beta-Aminoethylphenol; Phenol, p-(2-aminoethyl)-; Benzeneethanamine, 4-hydroxy-; Tyramine base; beta-Hydroxyphenylethylamine; NSC 249188; p-tyramine; [3H]tyramine
• Cross-matching ID:
  PubChem CID: 5610
  ChEBI ID: CHEMBL11608
  CAS Number: CAS 51-67-2
  TTD Drug ID: D0C5RZ
  VARIDT Drug ID: DR01389
  INTEDE Drug ID: DR2043

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Proteasome	1.96	0.00e+0	44/46 (95.65%)	PSMC5;PSMB5;PSMB4;...
Pyrimidine metabolism	1.95	0.00e+0	40/56 (71.43%)	NME4;RRM2;NME1;...
Cell cycle	1.87	5.53e-3	110/124 (88.71%)	SKP1;CDKN2C;CHEK2;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast

Nasopharyngeal carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
FIBRNPC	CVCL_UK07	Homo sapiens	10uM	6H, 24H	Hide ▲