| Primary immunodeficiency |
1.85 |
9.60e-2 |
33/38 (86.84%) |
CD40;CD79A;CD19;...
|
| Systemic lupus erythematosus |
1.72 |
1.84e-1 |
45/135 (33.33%) |
CD40;C1QA;CTSG;...
|
| Staphylococcus aureus infection |
1.65 |
2.43e-1 |
72/95 (75.79%) |
KRT19;DEFB1;KRT15;...
|
| Complement and coagulation cascades |
1.62 |
2.40e-1 |
76/85 (89.41%) |
FGB;FGA;CLU;...
|
| Tyrosine metabolism |
1.61 |
2.05e-1 |
30/36 (83.33%) |
TYRP1;DCT;ADH1B;...
|
| Ether lipid metabolism |
1.60 |
1.95e-1 |
32/49 (65.31%) |
PLPP3;PLAAT3;CHPT1;...
|
| Linoleic acid metabolism |
1.54 |
2.73e-1 |
21/29 (72.41%) |
PLAAT3;CYP2J2;ALOX15;...
|
| Gap junction |
1.46 |
4.60e-1 |
72/88 (81.82%) |
GNAS;TUBA1A;SRC;...
|
| Lysosome |
1.44 |
4.74e-1 |
115/128 (89.84%) |
CTSH;GALC;SORT1;...
|
| Peroxisome |
1.43 |
4.37e-1 |
72/82 (87.8%) |
PHYH;ACSL5;IDH2;...
|
| RNA polymerase |
1.43 |
4.26e-1 |
23/31 (74.19%) |
POLR2D;POLR1D;POLR2F;...
|
| Vitamin digestion and absorption |
1.42 |
4.02e-1 |
17/24 (70.83%) |
SLC5A6;APOB;TCN2;...
|
| Tryptophan metabolism |
1.41 |
4.11e-1 |
35/42 (83.33%) |
KYNU;IDO1;KMO;...
|
| Cholesterol metabolism |
1.37 |
5.19e-1 |
44/50 (88%) |
PLTP;LPL;SORT1;...
|
| Glycolysis / Gluconeogenesis |
1.37 |
4.93e-1 |
56/67 (83.58%) |
ALDOC;PFKL;ALDOA;...
|
| Thyroid hormone synthesis |
1.36 |
4.76e-1 |
66/75 (88%) |
GNAS;GPX3;FXYD2;...
|
| PPAR signaling pathway |
1.36 |
4.65e-1 |
66/74 (89.19%) |
FABP7;PLTP;LPL;...
|
| Histidine metabolism |
1.35 |
4.67e-1 |
16/22 (72.73%) |
HNMT;ALDH2;MAOA;...
|
| Amphetamine addiction |
1.31 |
5.65e-1 |
57/69 (82.61%) |
GNAS;FOSB;FOS;...
|
| Estrogen signaling pathway |
1.30 |
5.61e-1 |
119/137 (86.86%) |
KRT19;GNAS;SRC;...
|
| Coronavirus disease |
1.30 |
5.35e-1 |
215/232 (92.67%) |
FGB;FGA;FGG;...
|
| Drug metabolism |
1.30 |
5.22e-1 |
78/151 (51.66%) |
GSTT1;UGT2B28;FMO2;...
|
| Amoebiasis |
1.30 |
5.04e-1 |
99/102 (97.06%) |
GNAS;LAMA3;LAMC2;...
|
| Intestinal immune network for IgA production |
1.29 |
5.07e-1 |
38/48 (79.17%) |
CD40;CXCR4;TNFRSF17;...
|
| Renin secretion |
1.26 |
5.98e-1 |
61/69 (88.41%) |
GNAS;AGT;PTGER4;...
|
| B cell receptor signaling pathway |
1.25 |
5.94e-1 |
71/81 (87.65%) |
CD79A;FOS;IFITM1;...
|
| Fructose and mannose metabolism |
1.24 |
6.21e-1 |
30/33 (90.91%) |
ALDOC;PFKL;ALDOA;...
|
| Leukocyte transendothelial migration |
1.22 |
6.96e-1 |
90/114 (78.95%) |
RHOH;CXCR4;CD99;...
|
| Sphingolipid metabolism |
1.21 |
7.04e-1 |
32/49 (65.31%) |
GALC;PLPP3;NEU1;...
|
| Pentose phosphate pathway |
1.15 |
7.16e-1 |
25/30 (83.33%) |
ALDOC;PFKL;ALDOA;...
|
| ECM-receptor interaction |
-1.23 |
5.44e-1 |
80/88 (90.91%) |
ITGA6;ITGA1;ITGA2B;...
|
| Hematopoietic cell lineage |
-1.24 |
5.45e-1 |
90/99 (90.91%) |
IL1A;IL1R1;CD1D;...
|
| TGF-beta signaling pathway |
-1.24 |
5.52e-1 |
81/94 (86.17%) |
ROCK1;BMP2;EP300;...
|
| mTOR signaling pathway |
-1.24 |
5.61e-1 |
114/154 (74.03%) |
TSC1;RPS6;EIF4B;...
|
| Bladder cancer |
-1.25 |
5.65e-1 |
40/41 (97.56%) |
E2F3;MMP2;MDM2;...
|
| Starch and sucrose metabolism |
-1.25 |
5.62e-1 |
25/36 (69.44%) |
PYGL;SI;HKDC1;...
|
| Fatty acid degradation |
-1.26 |
5.49e-1 |
40/43 (93.02%) |
ACAA1;ACSL4;ACAT1;...
|
| Amyotrophic lateral sclerosis |
-1.26 |
5.46e-1 |
267/364 (73.35%) |
NDUFB5;GRIA1;TANK;...
|
| C-type lectin receptor signaling pathway |
-1.26 |
5.55e-1 |
93/104 (89.42%) |
BCL3;IRF9;PIK3CA;...
|
| RNA transport |
-1.26 |
5.64e-1 |
128/186 (68.82%) |
NMD3;EIF3B;GLE1;...
|
| Retrograde endocannabinoid signaling |
-1.27 |
5.61e-1 |
118/148 (79.73%) |
GRIA3;GABRB1;RIMS1;...
|
| Pathways of neurodegeneration |
-1.27 |
5.70e-1 |
354/475 (74.53%) |
GRIA3;CSNK2B;PSMD2;...
|
| Viral myocarditis |
-1.29 |
5.43e-1 |
53/60 (88.33%) |
ABL1;EIF4G3;HLA-G;...
|
| Ovarian steroidogenesis |
-1.30 |
5.45e-1 |
41/51 (80.39%) |
IGF1R;ADCY1;ADCY9;...
|
| Tuberculosis |
-1.30 |
5.61e-1 |
159/180 (88.33%) |
JAK2;CLEC4E;TLR6;...
|
| Synaptic vesicle cycle |
-1.30 |
5.69e-1 |
63/78 (80.77%) |
ATP6V1G1;STX3;UNC13B;...
|
| Kaposi sarcoma-associated herpesvirus infection |
-1.33 |
5.66e-1 |
172/193 (89.12%) |
CDK6;BAK1;MAP2K4;...
|
| Fatty acid elongation |
-1.34 |
5.46e-1 |
19/27 (70.37%) |
PPT2;ELOVL4;ELOVL2;...
|
| Type I diabetes mellitus |
-1.34 |
5.66e-1 |
38/43 (88.37%) |
GAD2;HLA-F;HSPD1;...
|
| Biosynthesis of unsaturated fatty acids |
-1.36 |
5.61e-1 |
21/27 (77.78%) |
TECR;FADS1;ACAA1;...
|
| Breast cancer |
-1.40 |
5.49e-1 |
119/147 (80.95%) |
CSNK1A1;KRAS;FZD4;...
|
| Inositol phosphate metabolism |
-1.41 |
5.58e-1 |
66/73 (90.41%) |
INPP5E;ITPK1;MINPP1;...
|
| Chronic myeloid leukemia |
-1.44 |
5.66e-1 |
72/76 (94.74%) |
CDK6;BAK1;TGFBR1;...
|
| Phagosome |
-1.51 |
4.25e-1 |
118/152 (77.63%) |
ATP6V0E1;SEC61G;ATP6V0D1;...
|
| Legionellosis |
-1.55 |
3.71e-1 |
51/57 (89.47%) |
HSPA6;HSPD1;CR1;...
|
| Apelin signaling pathway |
-1.57 |
3.55e-1 |
117/137 (85.4%) |
GNB2;CCN2;CALML4;...
|
| Thiamine metabolism |
-1.63 |
2.97e-1 |
12/15 (80%) |
ALPG;ALPL;ALPP;...
|
| Inflammatory bowel disease |
-1.69 |
2.41e-1 |
58/65 (89.23%) |
IL18RAP;MAF;IL1A;...
|
| Folate biosynthesis |
-1.72 |
2.63e-1 |
23/26 (88.46%) |
SPR;GPHN;AKR1B10;...
|
| Leishmaniasis |
-1.77 |
3.06e-1 |
67/77 (87.01%) |
IL1A;HLA-DPB1;IL1B;...
|
