Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM4ZLFD)

Drug Name
Glucosamine Drug Info
Synonyms
Chitosamine; GCS; Glucosamina; Glucosaminum; D-glucosamine; Glucosamina [INN-Spanish]; Glucosamine [USAN:INN]; Glucosaminum [INN-Latin]; Viartril-S; Beta-D-Glucosamine; Glucosamine (USAN/INN); Partially N-deacetylated poly-beta-1,6-N-acetyl-D-glucosamine; (2R,3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol; (2S,5R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol; (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol; 2-Amino-2-deoxy-D-glucose; 2-Amino-2-deoxy-beta-D-glucopyranose; 2-amino-2-deoxy-D-glucopyranose; 2-amino-2-deoxyglucose
Therapeutic ClassAntiinflammatory Agents
Cross-matching ID
PubChem CID
439213
ChEBI ID
CHEMBL47977
CAS Number
CAS 3416-24-8
TTD Drug ID
D07NSU
VARIDT Drug ID
DR00870
INTEDE Drug ID
DR0781

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Vibrio cholerae infection -1.74 4.21e-2 44/50 (88%) PDIA4;TCIRG1;SEC61A2;...
Hypertrophic cardiomyopathy -1.81 1.89e-2 81/90 (90%) ITGB7;SGCD;ITGA6;...
Dilated cardiomyopathy -1.86 6.01e-3 86/96 (89.58%) ITGB7;SGCD;ITGA6;...
African trypanosomiasis -1.86 7.21e-3 32/37 (86.49%) SELE;HPR;FASLG;...
Glyoxylate and dicarboxylate metabolism -1.93 3.01e-3 23/30 (76.67%) PCCA;GLDC;MDH1;...
Amino sugar and nucleotide sugar metabolism -1.99 0.00e+0 38/48 (79.17%) HK2;GNE;HK1;...
Ferroptosis -2.00 0.00e+0 36/41 (87.8%) PCBP1;STEAP3;GCLM;...
Mineral absorption -2.00 0.00e+0 48/60 (80%) TF;SLC30A1;SLC31A1;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast
Nasopharyngeal carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
FIBRNPC CVCL_UK07 Homo sapiens 10uM 6H, 24H