Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM58DGY)

• Drug Name: IM-12 Drug Info
• Synonyms: IM-12; 1129669-05-1; CHEMBL1254896; 3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione; 3-(4-fluorophenethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione; 3-[2-(4-fluorophenyl)ethylamino]-1-methyl-4-(2-methyl-1H-indol-3-yl)pyrrole-2,5-dione; IM 12; GTPL8017; SCHEMBL17378682; DTXSID20649091; AOB4090; MolPort-035-789-694; CHEBI:125616; HMS3653F15; BCP10769; EX-A2071; ZINC59086693; s7566; BDBM50326901; 2472AH; AKOS026750397; SB19269; CS-3399; CCG-208085; NCGC00386352-05; BC600587
• Cross-matching ID:
  PubChem CID: 25209788
  ChEBI ID: CHEMBL1254896
  CAS Number: CAS 1129669-05-1
  TTD Drug ID: D05SXF

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Pentose and glucuronate interconversions	2.01	0.00e+0	17/34 (50%)	AKR1B10;UGP2;UGT2B15;...
Cysteine and methionine metabolism	-1.94	3.97e-2	43/50 (86%)	AMD1;CBS;MDH2;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast

Nasopharyngeal carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
FIBRNPC	CVCL_UK07	Homo sapiens	10uM	6H, 24H	Hide ▲