Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM5BS98)

Drug Name
Ampiroxicam Drug Info
Synonyms Flucam; Nacyl; Nasil; CP-65703
Cross-matching ID
PubChem CID
2176
ChEBI ID
CHEMBL31210
CAS Number
CAS 99464-64-9
TTD Drug ID
D07OHO

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Fructose and mannose metabolism -1.93 1.12e-2 30/33 (90.91%) HK1;KHK;TKFC;...
Propanoate metabolism -2.02 0.00e+0 30/34 (88.24%) LDHB;BCKDHB;ACAT1;...
Valine, leucine and isoleucine degradation -2.06 0.00e+0 42/48 (87.5%) BCKDHB;ACAT1;ALDH7A1;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H
Liver
Hepatocellular carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HuH-7 CVCL_0336 Homo sapiens 8uM 72H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H