| Nitrogen metabolism |
1.89 |
6.90e-2 |
16/17 (94.12%) |
CA12;CA2;CA9;...
|
| IL-17 signaling pathway |
1.72 |
2.82e-1 |
84/94 (89.36%) |
MAPK6;FOSL1;S100A8;...
|
| Central carbon metabolism in cancer |
1.71 |
1.95e-1 |
67/70 (95.71%) |
G6PD;PKM;SLC2A1;...
|
| Ferroptosis |
1.71 |
1.47e-1 |
36/41 (87.8%) |
SLC7A11;GCLC;TFRC;...
|
| Fc epsilon RI signaling pathway |
1.60 |
2.99e-1 |
57/68 (83.82%) |
KRAS;ALOX5AP;FCER1A;...
|
| Glutathione metabolism |
1.56 |
3.39e-1 |
43/57 (75.44%) |
G6PD;GCLC;GCLM;...
|
| Viral protein interaction with cytokine and cytokine re... |
1.56 |
2.91e-1 |
84/100 (84%) |
IL2RB;CCR5;CCR7;...
|
| Osteoclast differentiation |
1.56 |
2.56e-1 |
117/127 (92.13%) |
FOSL1;JUND;SOCS1;...
|
| N-Glycan biosynthesis |
1.55 |
2.40e-1 |
38/50 (76%) |
GANAB;MAN1C1;B4GALT3;...
|
| Cytokine-cytokine receptor interaction |
1.52 |
2.79e-1 |
246/295 (83.39%) |
IL2RB;IL7R;CCR5;...
|
| Thiamine metabolism |
1.52 |
2.68e-1 |
12/15 (80%) |
AK1;ALPP;AK2;...
|
| Toll-like receptor signaling pathway |
1.47 |
3.69e-1 |
94/104 (90.38%) |
CXCL10;IFNAR1;CXCL9;...
|
| Phospholipase D signaling pathway |
1.47 |
3.49e-1 |
134/148 (90.54%) |
KRAS;PLPP3;FCER1A;...
|
| alpha-Linolenic acid metabolism |
1.47 |
3.26e-1 |
17/25 (68%) |
FADS2;PLA2G4A;ACAA1;...
|
| Glycosaminoglycan biosynthesis |
1.43 |
4.08e-1 |
40/58 (68.97%) |
CHST2;EXT1;B4GALT3;...
|
| Mineral absorption |
1.41 |
4.34e-1 |
48/60 (80%) |
FTH1;ATP1B1;FTL;...
|
| Ubiquinone and other terpenoid-quinone biosynthesis |
1.41 |
4.09e-1 |
9/11 (81.82%) |
NQO1
|
| Glycosaminoglycan degradation |
1.41 |
4.01e-1 |
19/19 (100%) |
SGSH;HGSNAT;GUSB;...
|
| Hematopoietic cell lineage |
1.41 |
3.86e-1 |
90/99 (90.91%) |
TFRC;IL7R;CD9;...
|
| Renal cell carcinoma |
1.38 |
4.35e-1 |
68/69 (98.55%) |
SLC2A1;VEGFA;KRAS;...
|
| Sulfur metabolism |
1.38 |
4.18e-1 |
9/10 (90%) |
SELENBP1;ETHE1;PAPSS1;...
|
| Regulation of actin cytoskeleton |
1.38 |
4.08e-1 |
185/218 (84.86%) |
PFN2;ENAH;KRAS;...
|
| ErbB signaling pathway |
1.37 |
4.21e-1 |
79/85 (92.94%) |
KRAS;SRC;GRB2;...
|
| Hepatocellular carcinoma |
1.35 |
4.49e-1 |
135/168 (80.36%) |
NQO1;KRAS;ACTB;...
|
| Signaling pathways regulating pluripotency of stem cell... |
1.35 |
4.34e-1 |
110/143 (76.92%) |
KRAS;GRB2;FGFR3;...
|
| Rap1 signaling pathway |
1.35 |
4.20e-1 |
184/210 (87.62%) |
ADORA2B;PFN2;FPR1;...
|
| Natural killer cell mediated cytotoxicity |
1.35 |
4.08e-1 |
99/131 (75.57%) |
KRAS;GRB2;GZMB;...
|
| Lysosome |
1.33 |
4.36e-1 |
115/128 (89.84%) |
CTSZ;LAMP3;CTSH;...
|
| Fluid shear stress and atherosclerosis |
1.33 |
4.27e-1 |
123/139 (88.49%) |
NQO1;VEGFA;ACTB;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
1.29 |
4.44e-1 |
62/70 (88.57%) |
SRC;MET;PAK1;...
|
| Cysteine and methionine metabolism |
-1.27 |
4.60e-1 |
43/50 (86%) |
GSS;MTAP;APIP;...
|
| Purine metabolism |
-1.28 |
4.35e-1 |
102/129 (79.07%) |
NME7;PFAS;RRM1;...
|
| Phenylalanine metabolism |
-1.29 |
4.40e-1 |
14/17 (82.35%) |
HPD;TAT;DDC;...
|
| Fatty acid degradation |
-1.30 |
4.13e-1 |
40/43 (93.02%) |
CPT2;ECHS1;HADH;...
|
| Transcriptional misregulation in cancer |
-1.30 |
4.25e-1 |
158/192 (82.29%) |
MEIS1;TGFBR2;PDGFA;...
|
| Aldosterone synthesis and secretion |
-1.31 |
4.25e-1 |
85/98 (86.73%) |
CREB3L1;CREB3L2;CYP11B2;...
|
| Selenocompound metabolism |
-1.31 |
4.38e-1 |
11/17 (64.71%) |
SEPHS1;KYAT3;PAPSS2;...
|
| Pyrimidine metabolism |
-1.33 |
4.20e-1 |
40/56 (71.43%) |
CMPK1;TK2;RRM2;...
|
| Pyruvate metabolism |
-1.33 |
4.26e-1 |
41/47 (87.23%) |
PCK1;ALDH9A1;GRHPR;...
|
| cGMP-PKG signaling pathway |
-1.35 |
3.94e-1 |
145/167 (86.83%) |
FXYD2;NFATC3;GNAI2;...
|
| Alanine, aspartate and glutamate metabolism |
-1.35 |
4.03e-1 |
27/37 (72.97%) |
CPS1;GPT;ADSL;...
|
| Taurine and hypotaurine metabolism |
-1.38 |
3.33e-1 |
8/11 (72.73%) |
GAD1;CSAD;GGT5;...
|
| Non-homologous end-joining |
-1.38 |
3.50e-1 |
11/13 (84.62%) |
RAD50;DCLRE1C;MRE11;...
|
| Coronavirus disease |
-1.41 |
3.07e-1 |
215/232 (92.67%) |
IL1B;RPL35A;TYK2;...
|
| Diabetic cardiomyopathy |
-1.43 |
2.83e-1 |
162/203 (79.8%) |
TGFBR2;SDHB;CAMK2G;...
|
| Renin secretion |
-1.43 |
2.90e-1 |
61/69 (88.41%) |
AQP1;GNAI3;EDNRA;...
|
| Hedgehog signaling pathway |
-1.45 |
2.74e-1 |
43/56 (76.79%) |
SPOP;KIF3A;SMO;...
|
| Drug metabolism |
-1.46 |
2.59e-1 |
78/151 (51.66%) |
CMPK1;TK2;RRM2;...
|
| p53 signaling pathway |
-1.48 |
2.44e-1 |
63/73 (86.3%) |
GADD45B;CCND3;RRM2;...
|
| Retinol metabolism |
-1.49 |
2.55e-1 |
41/68 (60.29%) |
ALDH1A2;CYP2C8;ALDH1A3;...
|
| Nicotinate and nicotinamide metabolism |
-1.50 |
2.59e-1 |
25/35 (71.43%) |
QPRT;NMRK2;NADSYN1;...
|
| Complement and coagulation cascades |
-1.50 |
2.77e-1 |
76/85 (89.41%) |
C1QA;CR1;SERPINE1;...
|
| Prion disease |
-1.50 |
3.11e-1 |
209/273 (76.56%) |
PSMD6;CREB3L1;COX7A2;...
|
| Glycine, serine and threonine metabolism |
-1.53 |
2.92e-1 |
31/40 (77.5%) |
PSPH;PSAT1;SARDH;...
|
| Regulation of lipolysis in adipocytes |
-1.57 |
2.48e-1 |
52/55 (94.55%) |
GNAI2;ADCY7;ADCY3;...
|
| Oxidative phosphorylation |
-1.57 |
2.83e-1 |
93/133 (69.92%) |
ATP6V1B2;NDUFA3;ATP5PF;...
|
| Tyrosine metabolism |
-1.58 |
3.43e-1 |
30/36 (83.33%) |
TYRP1;AOC3;ADH1C;...
|
| Butanoate metabolism |
-1.62 |
2.90e-1 |
23/28 (82.14%) |
BDH2;BDH1;EHHADH;...
|
| One carbon pool by folate |
-1.67 |
2.21e-1 |
15/20 (75%) |
AMT;SHMT1;MTHFD2;...
|
| Homologous recombination |
-1.70 |
3.32e-1 |
35/41 (85.37%) |
POLD2;RAD51;SSBP1;...
|
